Skip to main content
Log in

Pulmonary artery obstruction with fibrosing mediastinitis

  • Published:
Lung Aims and scope Submit manuscript

Abstract

A 48-year-old female was found to have fibrosing mediastinitis with pulmonary artery obstruction 4 years after an episode of right upper lobe pulmonary infarction. Biopsy material from the right upper lobe obtained at the time of the initial episode suggested venous obstruction. Acquired pulmonary artery occlusion secondary to fibrosing mediastinitis is a rare entity. This patient and twelve other reported cases are contrasted.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Andrews, E. C.: Five cases of an undescribed form of pulmonary interstitial fibrosis caused by obstruction of the pulmonary veins. Bull. Johns Hopkins Hosp.100, 28–42 (1957)

    PubMed  Google Scholar 

  2. Arnett, E., Bacos, J. M., Macher, A. M., Marsh, H. B., Savage, D. D., Fulmer, J. D., Roberts, W. C.: Fibrosing mediastinitis causing pulmonary arterial hypertension without pulmonary venous hypertension. Am. J. Med.63, 634–643 (1977)

    Article  CAS  PubMed  Google Scholar 

  3. Cheris, D. N., Dadly, J. L.: Fibrosing mediastinitis: A unusual cause for cor pulmonale. Am. J. Roentgen.100, 328–331 (1967)

    Article  CAS  PubMed  Google Scholar 

  4. Cosio, F. G., Gobel, F. L., Harrington, D. P., Sako, Y.: Pulmonary arterial stenosis with wide splitting of the second heart sound due to mediastinal fibrosis. Am. J. Cardiol.31, 372–376 (1973)

    Article  CAS  PubMed  Google Scholar 

  5. Delbanco, T. L., Sadler, T. R., Medina, J. R., Nelson, W. P.: Bilateral pulmonary artery obstruction due to fibrosing mediastinitis. Mil. Med.141, 335–339 (1976)

    CAS  PubMed  Google Scholar 

  6. del Castillo, J., Granfrancesco, H., Mannix, E. P., Jr.: Pulmonic stenosis due to compression by sternal chondrosarcoma. J. Thorac. Cardiovasc. Surg.52, 255–260 (1966)

    PubMed  Google Scholar 

  7. Dotter, C. T.: Acquired abnormalities of the pulmonary arteries. In: Angiography, vol. 1, 2nd ed., p. 477 (ed. H. L. Abrams). Boston: Little, Brown, 1971

    Google Scholar 

  8. Drachler, D. H., Park, W. W.: Acquired right ventricular outflow tract obstruction. Am. Heart J.82, 536–540 (1971)

    Article  CAS  PubMed  Google Scholar 

  9. Dupont, H. L., Varco, R. L., Winchell, C. P.: Chronic fibrous mediastinitis simulating pulmonic stenosis, associated with inflammatory pseudotumor of the orbit. Am. J. Med.44, 447–452 (1968)

    Article  CAS  PubMed  Google Scholar 

  10. Goodwin, R. A., Nickell, J. A., Des Prez, R. M.: Mediastinal fibrosis complicating healed primary histoplasmosis and tuberculosis. Medicine51, 227–246 (1972)

    Article  CAS  PubMed  Google Scholar 

  11. Gottlief, L. S., Turner, A. F.: Swyer-James (Macleod’s) syndrome: Variations in pulmonary-bronchial arterial blood flow. Chest69, 62–66 (1976)

    Article  Google Scholar 

  12. Nelson, W. P., Lundberg, G. D., Dickerson, R. B.: Pulmonary artery obstruction and cor pulmonale due to chronic fibrous mediastinitis. Am. J. Med.38, 279–285 (1965)

    Article  CAS  PubMed  Google Scholar 

  13. Salyer, J. M., Harrison, H. N., Winn, D. F., Taylor, R. R.: Chronic fibrous mediastinitis and superior vena caval obstruction due to histoplasmosis. Dis. Chest35, 364–377 (1959)

    Article  CAS  PubMed  Google Scholar 

  14. Soderberg, G.: Om strikture av arteria pulmonalis genom skrumpnande mediastinit. Nord. Med.28, 2051–2059 (1945)

    Google Scholar 

  15. Tourniaire, A., Treppox, M., Tartulier, M., Deyrieuz, F., Van Straaten, G.: Coeur pulmonaire chronique par compression arterielle pulmonaire dans la maladie du hile d’ origine ganglionnaire. Arch. mal. coeur51, 960–967 (1958)

    CAS  PubMed  Google Scholar 

  16. Yacoub, M. H., Thompson, V. C.: Chronic idiopathic pulmonary hilar fibrosis: A clinicopathological entity. Thorax26, 365–377 (1971)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Requests for reprints and correspondence should be addressed to Dr. E. Neil Schachter, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut 06510, USA.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Zorn, S.K., Schachter, E.N., Smith, G.J.W. et al. Pulmonary artery obstruction with fibrosing mediastinitis. Lung 155, 91–100 (1978). https://doi.org/10.1007/BF02730683

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02730683

Key words

Navigation