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Mechanisms of acquired resistance to plague in mice infected byYersinia enterocolitica O3

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Abstract

Yersinia enterocolitica, serogroup O3, injected either intravenously or intragastrically to mice, induced acquired resistance toYersinia pestis. The digestive infection byY. enterocolitica O3 was mostly located into the Peyer’s patches and the ileum wall; the blood, the mesenteric lymph node, and the spleen were not invaded. Serum fromY. enterocolitica O3 convalescing mice failed to protect passively againstY. pestis. In contrast, lymphoid cells from the stimulated Peyer’s patches permitted transfer of efficient bactericidal activity againstY. pestis.

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Alonso, JM., Vilmer, E., Mazigh, D. et al. Mechanisms of acquired resistance to plague in mice infected byYersinia enterocolitica O3. Current Microbiology 4, 117–122 (1980). https://doi.org/10.1007/BF02602904

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