Abstract
The role of aspirin as a risk factor in the occurrence of intracranial bleeding following head injury was investigated. Chronic subdural hematoma appears to be a suitable model for the evaluation of risk factors in the development of hemorrhage. The most common risk factors found in our study were, apart from age, chronic alcohol abuse (28%), consumption of cumarin-derivates (21%), aspirin (13%), and heparin (5%). A patient undergoing aspirin treatment must be considered at risk of development of chronic subdural hematoma. Aspirin should not be prescribed to patients with post-traumatic headaches.
Similar content being viewed by others
References
Hirsch J, V Fuster, E Salzman: Dose antiplatelet agents: the relationship among side effects, and antithrombotic effectiveness. Chest 89 (1986) 4S-10S
Matsumori K, M Yoshioka: Kinetics of prostaglandins and its significance in chronic subdural hematoma. Neurol Med Chir (Tokyo) 27 (1987) 498–504
Olson JD, HH Kaufman, J Moake, THW O'Gorman, K Hoots, K Wagner, CK Brown, PHL Gildenberg: The incidence of hemostatic abnormalities in patients with head injuries. Neurosurgery 24 (1989) 825–832
Sathiropas P, GA Marbet, S Sahaphong, F Duckert: Detection of small inhibitory effects of acetylsalicylic acid (ASA) by platelet impedance aggregometry in whole blood. Thrombosis Res 51 (1988) 55–62
Spallone A, R Giuffre, FM Gagliardi, R Vagnozzi: Chronic subdural hematoma in extremely aged patients. Europ Neurol 29 (1989) 18–22
Wier B, P Gordon: Factors affecting coagulation: fibrinolysis in chronic subdural fluid collections. J Neurosurg 58 (1983) 242–245
Wintzen AR, JGP Tusssen: Subdural hematoma and oral anticoagulant therapy. Arch Neurol 39 (1982) 69–72
Wolfe LS, OA Mamer: Measurement of prostaglandin F2 alpha levels in human cerebrospinal fluid in normal and pathological conditions. Prostaglandins 9 (1975) 183–192
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Reymond, M.A., Marbet, G., Radii, E.W. et al. Aspirin as a risk factor for hemorrhage in patients with head injuries. Neurosurg. Rev. 15, 21–25 (1992). https://doi.org/10.1007/BF02352062
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF02352062