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Abnormal subjective experiences in schizophrenia: its relationships with neuropsychological disturbances and frontal signs

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Abstract

The prevalence of abnormal subjective experiences is high in schizophrenic patients. This study starts from the hypothesis that these subjective disorders are associated with cognitive disturbances. In order to test this hypothesis a study was carried out on 40 patients who were diagnosed as suffering from schizophrenia according to RDC and DSM-III-R criteria. They were consecutively admitted due to a recrudescence of their symptomatology. Version 3 of the Frankfurt Complaint Questionnaire, adapted for Spanish by the authors, was used as an instrument for the assessment of subjective experiences. Eight patients refused to answer the questionnaire. A neuropsychological battery, including the Mini-Mental State, some subtests from the WAIS, Bender's visual-motor test, Rey's Complex Figure, and the Trail Making Test, was used. Frontal neurological signs were evaluated. The abnormal subjective experiences of schizophrenics presented a close association with neuropsychological disturbances and, to a lesser degree, of intensity with frontal neurological signs. Regression analyses by means of stepwise method and partial correlation analyses were undertaken. Many significant relationships between subjective experiences and cognitive disturbances persisted after controlling the influence of age, gender, education, lack of insight, neuroleptic doses, and biperidene doses.

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References

  • Addington J, Addington D, Marticka-Tyndale E (1991) Cognitive functioning and positive and negative symptoms in schizophrenia. Schizophr Res 5:123–134

    Google Scholar 

  • American Psychiatric Association (1987) Diagnostic and statistical manual of mental disorders, (DSM-III-R), 3rd ed-revised. American Psychiatric Press, Washington DC

    Google Scholar 

  • Andreasen NC, Olsen S (1982) Negative versus positive schizophrenia: definition and validation. Arch Gen Psychiatry 39: 789–794

    Google Scholar 

  • Andreasen NC (1990) Positive and negative symptoms in schizophrenia. A critical reappraisal. Arch Gen Psychiatry 47:615–621

    Google Scholar 

  • Bender L (1947) Instructions for the use of Visual Motor Gestalt Test. American Orthopsychiatric Association, New York. (El test guestáltico visuomotor de Bender. Uso y aplicaciones clínicas, 1974, Sexta edition, Paidos, Buenos Aires)

    Google Scholar 

  • Benson DF, Stuss DT (1982) Motor abilities after frontal leukotomy. Neurology 32:1353–1357

    Google Scholar 

  • Bitter I, Jaeger J, Agdeppa J, Volavka J (1989) Subjective symptoms: part of the negative syndrome of schizophrenia? Psychopharm Bull 25:180–185

    Google Scholar 

  • Brenner HD (1989) The treatment of basic psuchological dysfunctions from a systemic point of view. Br J Psychiatry 155 (Suppl 5):74–82

    Google Scholar 

  • Chapman J (1966) The early symptoms of schizophrenia. Br J Psychiatry 112:225–231

    Google Scholar 

  • Christensen A (1978) Luria's neuropsychological investigation. led. Munksgaard, Copenhagen. (El diagnóstico neuropsicológico de Luria, ed Pablo del Río, Madrid)

    Google Scholar 

  • Crow TJ (1980) Molecular pathology of schizophrenia: more than one disease. Br Med J 280:66–68

    Google Scholar 

  • Cuesta MJ, Peralta V (1994): Lack of, insight in schizophrenia. Schizophr Bull 20(2):359–366

    Google Scholar 

  • Cuesta MJ, Peralta V (1995) Cognitive disorders in the positive, negative and disorganization schizophrenic syndromes. Psychiatry Res 58:227–235

    Google Scholar 

  • Cutting J, Dunne F (1989) Subjective experience of schizophrenia. Schizophr Bull 15:217–231

    Google Scholar 

  • Davis JM (1976) Comparative drugs and costs of antipsychotic medication. Arch Gen Psychiatry 33:858–861

    Google Scholar 

  • De Leon J, Wilson WH, Simpson GM (1991) Negative symptoms, defect state and Huber's basic symptoms: a comparison of the concepts. Psychiatry Q 62:277–297

    Google Scholar 

  • Ebel H, Gross G, Klosterkötter J, Huber G (1989) Basic symptoms in schizophrenic and affective psychoses. Psychopathology 22: 224–232

    Google Scholar 

  • Faustman WO, Moses JA, Ringo DL, Newcomer JW (1991) Lefthandedness in male schizophrenic patients is associated with increased impairment on the Luria-Nebraska neuropsychological battery. Biol Psychiatry 30:326–334

    Google Scholar 

  • Goldberg E, Bilder R, Jaeger J (1987) The executive dyscontrol battery and its applications. J Clin Exp Neuropsychol 9:38–48

    Google Scholar 

  • Green M, Walker E (1985) Neuropsychological performance and positive and negative symptoms in schizophrenia. J Abnorm Psychol 94:460–469

    Google Scholar 

  • Gross G, Huber G, Klosterkötter J et al. (1987) Bonner Skala für die Beurteilung von Basissymtomen. (SABS: Bonn Scale for the Assessment of Basic Symptoms). Springer, Berlin Heidelberg New York

    Google Scholar 

  • Grove WM, Andreasen NC (1982) Simultaneous tests of many hypotheses in exploratory research. J Nerv Ment Dis 170(1):3–9

    Google Scholar 

  • Guy W, Ban TA (1979) The AMDP System. Springer, Berlin Heidelberg New York

    Google Scholar 

  • Hasse-Sender I, Gross G, Huber G et al. (1982) Testpsychologische Untersuchungen in Bassistadien und reinen Residualzuständen schizophrener Erkrankungen. Arch Psychiatr, Nervekr 231:235–249

    Google Scholar 

  • Heinrichs DW, Buchanan RW (1988) Significance and meaning of neurological signs in schizophrenia. Am J Psychiatry 145:11–18

    Google Scholar 

  • Huber G (1957) Pneumenzephalographische und psychopathologische Bilder bei endogenen psychosen. Springer, Berlin Heidelberg New York

    Google Scholar 

  • Huber G (1966) Reine Defectsyndrome und Bassistadien endogener Psychosen. Fortschr Neurol Psychiatr 34:409–426

    Google Scholar 

  • Keilp JG, Seeney JA, Jacobsen P, Solomon C, St. Louis L, Deck M, Frances A, Mann J (1988) Cognitive impairment in schizophrenia: specific relations to ventricular size and negative symptomatology. Biol Psychiatry 24:47–55

    Google Scholar 

  • Kennard MA (1960) Value of equivocal signs in neurological diagnosis. Neurology 10:753–764

    Google Scholar 

  • Kick MA (1991) Psychopathologie und Verlauf der Postakuten Schizophrenie. Springer, Berlin Heidelberg New York

    Google Scholar 

  • Koehler K, Sauer H (1984) Huber's basic symptoms: another approach to negative psychopathology in schizophrenia. Compr Psychiatry 25:176–182

    Google Scholar 

  • Kolakowska T, Williams AO, Ardern M (1985) Schizophrenic with good and poor outcome. III. Neurological “soft” signs. Cognitive impairment and their clinical significance. Br J Psychiatry 146:348–357

    Google Scholar 

  • Kolb B, Winshaw Q (1983) Performance of schizophrenic patients on test sensibles to left and right frontal, temporal or parietal function in neurological patients. J Nerv Ment Dis 171:435–443

    Google Scholar 

  • Kraepelin E (1919). Dementia praecox and paraphrenia (tranls. by R. Mary Barclay from Psychiatrie, 8th edn, 1913). Livingstone Edinburgh

    Google Scholar 

  • Landmark I (1982) A manual for the assessment of schizophrenia. Acta Psychiatr Scand 298 (Suppl 65):1–88

    Google Scholar 

  • Lobo Ac Ezquerra J, Escobar V, Sala JM, Seva A (1979) El mini examen cognoscitivo: Un test simple y práctico para dectectar defectos cognitivos. Comunicación Psiquiátrica 3:73–79

    Google Scholar 

  • Liddle PF (1987) Schizophrenic syndromes, cognitive performance and neurological dysfunction. Psychol Med 17:49–57

    Google Scholar 

  • Liddle PF, Barnes TRE (1988) The subjective experience of deficits in schizophrenia. Compr Psychiatry 29:157–164

    Google Scholar 

  • Manschreck TC, Ames D (1984) Neurological features and psychopathology in schizophrenic disorders. Biol Psychiatry 19: 703–719

    Google Scholar 

  • Merriam AE, Kay S, Opler LA, Kushner SF, van Praag M (1990) Neurological signs and the positive-negative dimension in schizophrenia. Biol Psychiatry 28:181–192

    Google Scholar 

  • McGie A, Chapman J (1961) Disorders of attention and perception in early schizophrenia. Br J Med Psychol 34:103–116

    Google Scholar 

  • Mosher L, Pollin W, Stanebau J (1971) Identical twins discordant for schizophrenia: neurological findings. Arch Gen Psychiatry 24:422–430

    Google Scholar 

  • Mundt CH, Kasper S, Huerkamp M (1989) The diagnostic specificity of negative symptoms and their psychopathological context. Br J Psychiatry 155 (Suppl 7):32–36

    Google Scholar 

  • Norusis MJ (1986) The Statistical Package for Social Sciences (SPSS/PC+). Manual of reference. SPSS Inc, Chicago

    Google Scholar 

  • Oldfield RC (1971) The assessment and analysis of handedness: the Edinburgh Inventory. Neuropsychologia 9:97–113

    Google Scholar 

  • Owens DG, Johnstone EC (1980) The disabilities of chronic schizophrenia — their nature and factors contributing to their development. Br J Psychiatry 136:384–395

    Google Scholar 

  • Peralta V, Cuesta MJ (1989a) Trastornos cognitivos en la esquizofrenia: valoración por medio del inventario psicopatológico de Frankfurt. Resultados iniciales. Actas Luso-Españolas de Neurología, Psiquiatría y Ciencias Afines 17:255–262

    Google Scholar 

  • Peralta V, Cuesta MJ (1989b) El valor pronóstico de los trastornos cognitivos en la esquizofrenia evaluados por medio del Inventario Psicopatológico de Frankfurt. Revista de Psiquiatría de la Facultad de Medicina de Barcelona 16:295–302

    Google Scholar 

  • Peralta V, Cuesta MJ (1991) Schneiderian versus Bleurian schizophrenia and basic symptoms. Psychopathology 24:151–157

    Google Scholar 

  • Peralta V, Cuesta MJ (1994) Subjective experiences in schizophrenia: a critical review. Compr Psychiatry 35:198–204

    Google Scholar 

  • Petho B, Bitter I (1985) Types of complaints in psychiatric and internal medical patients. Psychopathology 18:241–253

    Google Scholar 

  • Reitan RM (1978) Manual for administration of neuropsychological test batteries for adult and children. Reitan Neuropsychology Laboratories, Inc, Tucson, Arizona

    Google Scholar 

  • Rey A (1959) Test de Copie et de Reproduction de Mémoire de Figures Géometriques Complexes. [El test de copia de una Figura Compleja (1980) TEA, Madrid]

  • Rochford JM, Detre T, Tucker GJ, Harrow M (1970) Neuropsychological impairments in functional diseases. Arch Psychiatry 22:114–119

    Google Scholar 

  • Royall DR, Mahurin RK, True JE, Anderson B, Brock IP, Freeburger L, Miller A (1993) Executive impairment among the functionally dependent: comparisons between schizophrenic and elderly subjects. Am Psychiatry 150:1813–1819

    Google Scholar 

  • Schröder J, Niethammer R, Geider FJ, Reitz C, Binkert M, Jauss M, Sauer H (1992) Neurological soft signs in schizophrenia. Schizophr Res 6:25–30

    Google Scholar 

  • Selten JP, Sijben AE, van den Bosch RJ (1991) Subjective experience of negative symptoms. Biol Psychiatry 29:404S

    Google Scholar 

  • Spitzer RL, Endicott J, Robins E (1978) Research diagnostic criteria (RDC) for a selected group of functional disorders, 3rd edn. New York State Psychiatric Institute, New York

    Google Scholar 

  • Strauss JS, Carpenter WT Jr (1974) The prediction of outcome in schizophrenia. II Relationship between predictor and outcome variables. Arch Gen Psychiatry 31:37–42

    Google Scholar 

  • Sülwold L (1985) Schizophrenic basic disturbances: psychological aspects the type of “psychological deficiency”. In: Pichot P, Berner P, Wolf R, Thau K (eds) Psychiatry. The state of the art, vol 1 Plenum Press, New York and London, pp 473–475

    Google Scholar 

  • Sülwold L (1986) Frankfurter Bechswerde-Fragebogen (3). In: Sülwold L, Huber G (eds) Schizophrene Bassistörungen. Springer, Berlin Heidelberg New York

    Google Scholar 

  • van den Bosch RJ, Rozendaal N (1988) Subjective cognitive dysfunction, eye tracking and slow brain potentials in schizophrenic and schizoaffective patients. Biol Psychiatry 24:741–746

    Google Scholar 

  • Wagman AMI, Heinrichs DW, Carpenter WT (1987) Deficit and nondeficit forms of schizophrenia: Neuropsychological evaluation. Psychiatry Res 22:319–330

    Google Scholar 

  • Wechsler D (1955) Manual for the Wechsler Adult Intelligence Scale. The Psychological Corporation, New York (WAIS, 1990, TEA Ediciones SA, 8a edición).

    Google Scholar 

  • Woods BT, Berman KF, Zec RF (1986) Physiologic dysfunctions of dorsolateral prefrontal cortex in schizophrenia. I. Regional cerebral blood flow evidence. Arch Gen Psychiatry 43:647–663

    Google Scholar 

Download references

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Authors and Affiliations

  1. Psychiatric Unit, Virgen del Camino Hospital, C/Irunlarrea 6, E-31008, Pamplona, Spain

    Manuel J. Cuesta, Víctor Peralta & Jose A. Juan

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  1. Manuel J. Cuesta
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  2. Víctor Peralta
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  3. Jose A. Juan
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Cuesta, M.J., Peralta, V. & Juan, J.A. Abnormal subjective experiences in schizophrenia: its relationships with neuropsychological disturbances and frontal signs. Eur Arch Psychiatry Clin Nuerosci 246, 101–105 (1996). https://doi.org/10.1007/BF02274900

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  • DOI: https://doi.org/10.1007/BF02274900

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