Skip to main content
Log in

Hormon- und Zytokinrezeptoren im Tumorgewebe — Therapeutische Entscheidungshilfen oder Fiktion?

  • Gynäkologische Onkologie
  • Gynäkologische Onkologie
  • Published:
Archives of Gynecology and Obstetrics Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Literatur

  1. Bauknecht, T.: EGF receptor (EGF-R) analysis in endometrial carcinoma In: Kleine, W. et al. (eds): Therapie des Endometriumkarzinoms Springer Verlag Berlin Heidelberg, 65, 1991

    Google Scholar 

  2. Bauknecht, T., Janz, J., Kohler, M., Pfleiderer, A.: Human ovarian carcinomas: Correlation of malignancy and survival with the expression of epidermal growth factor receptor and EGF-like factors Med. Oncol. Pharmacother. 6, 121, 1989.

    CAS  Google Scholar 

  3. Emons,G., Ortmann,O., Schulz,K.-D.: Rolle der endokrinen Therapie beim Ovarialkarzinom Gynäkol. Praxis (im Druck) 1992

  4. Fuqua, S.A.W., Fitzgerald, S.D., CHamness, G.C:, Tandon, A.K., McDonnell, D:P., Nawaz, Z., O'Malley, B.W:, McGuire, W.L.: Variant human breast tumor estrogen receptor with constitutive transcriptional activity Cancer Res. 51, 105, 1991

    CAS  PubMed  Google Scholar 

  5. Hackenberg, R., Hofmann, J., Hölzel, F., Schulz, K.-D.: Stimulatory effects of androgen and antiandrogen on the in vitro proliferation of human mammary carcinoma cells Clin. Oncol. 114, 593, 1988

    CAS  Google Scholar 

  6. Hackenberg, R., Hofmann, J., Wolff, G., Hölzel, F., Schulz, K.-D.: Down regulation of androgen receptor by progestins and interference with estrogenic or androgeneic stimulation of mammary carcinoma cell growth J. Cancer Res. Clin. Oncol. 116,492, 1990

    Article  CAS  PubMed  Google Scholar 

  7. Hackenberg, R., Lüttchens, S., Hofmann, J., Kunzmann, R., Hölzel, F., Schulz, K.-D.: Androgen sensitivity of a new human breast cancer cell line MFM-223 Cancer Res. 51, 5722–5727, 1991

    CAS  PubMed  Google Scholar 

  8. Hackenberg,R., Hawighorst,Th., Hushmand Nia,A., Schulz,K.-D.: Regulation of androgen receptor mRNA and protein level by steroid hormones in human mammary cancer cells J. Steriod. Biochem. Mol. Biol. (im Druck, 12/1992)

  9. Hofmann, J., Hackenberg, R., Musiol, A., Wolff, G., Hölzel, F., Schulz, K.-D.: Binding proteins for insuline-like growth factors secreted by human ovarian carcinoma cells J. Cancer Res. Clin. Oncol. 116,2, 1990

    Google Scholar 

  10. Hofmann,J., Wegmann,B., Hackenberg,R., Kunzmann,R., Schulz,K.-D., Havemann,K.: Production of insulun-like growth factor binding proteins by human ovarian carcinoma cells J. Clin. Endocr. (im Druck)

  11. Jensen,E.V., DeSombre,E.R., Jungblut,P.W.: Estrogen receptors in hormone-responsive tissues and tumors In: Endogenous factors influencing host-tumor balance Nissler,R.W., Dao,T.L., Wood,S. (eds), Univ Chicago Press, 15 ff, 1967

  12. Kaiser, R., Schulz, K.-D., Maass, H.: Hormonale Behandlung von Genital- und Mammatumoren Thieme Verlag Stuttgart New York 1991

    Google Scholar 

  13. King, R.J.B.: Effects of steroid hormones and related compounds on gene transcription Clin. Endocr. 36, 1, 1992

    CAS  PubMed  Google Scholar 

  14. Klijn, J.G.M., Berns, P.M.J.J., Schmitz, P.J.M., Foekens, J.A.: The clinical significance of Epidermal Growth Factor Receptor (EGF-R) in human breast cancer: A review on 5253 patients Endocrine Reviews 13, 3, 1992

    Article  CAS  PubMed  Google Scholar 

  15. Lippmann, M.E., Dickson, R.B., Gelmann, E.P., Rosen, N., Krabbe, C. et al: Human breast carcinoma cells produce growth regulatory peptides Progr. Cancer Research and Therapy 35, 203–213, 1988

    Google Scholar 

  16. Manni, A., Wei, L., Kim, J., Badger, B., Zaenglein, A., Leighton, J.: Expression and regulation of insulin-like growth factor binding proteins by breast cancer cells International Conference on Clinical Use of Aromatase Inhibitors, Bologna/Italy, Juni 1992

  17. Maass, H., Engel, G., Hohmeister, H., Lehman, F., Trams, G.: Estrogen receptors in human breast cancer tissue Am. J. Obstet. Gynecol. 113, 377, 1972

    CAS  PubMed  Google Scholar 

  18. Maass, H., Jonat, W., Steroidrezeptoren in Mammakarzinomen Bericht über ein Consensus-Meeting im Nat. Inst. of Health, USA, Geburth. u. Frauenheilk. 39, 14, 1979

    Google Scholar 

  19. Rao, R., Slotman, B.J.: Endocrine factor in common epithelial ovarian cancer Endocrine Reviews 12, 14, 1991

    CAS  PubMed  Google Scholar 

  20. Satyaswaroop,P.G.: Heterogenity of the progesterone receptor in endometrial carcinoma Symp. on „Normal and Pathologycal Endometrium“, Marburg, April 1992

  21. Scambia, G., Panici, P.B., Battaglia, F., Ferrandina, G., Baiocchi, G., Gallo, A., Sica, G., Mancuso, S.: Effect of recombinant human interferon alpha on receptors for steroid hormones and epidermal growth factor in patients with endometrial cancer Eur. J. Cancer 27, 51, 1991

    CAS  PubMed  Google Scholar 

  22. Schmidt-Rhode, P., Schulz, K.-D., Reusch, K., Würz, H.: Die Wirksamkeit einer endokrinen Therapie beim metastasierenden Mammakarzinom in Korrelation zum Steroidhormon — Rezeptorbefund In: Jonat, W., Maass, H. (eds): Steroidhormonrezeptoren im Mammakarzinom, Enke Verlag Stuttgart, S. 160, 1982

    Google Scholar 

  23. Schulz, K.-D., Haselmayer, B., Hölzel, F.: The influence of clomid and its isomers on dimethylben zanthracene induced rat mammary tumors Acta Endocr. (kbh) Suppl. 138, 236, 1969

    Google Scholar 

  24. Schmutzler,R.K., Lehrer,S., Krebs,D., Schachter,B.S.: Klinische Bedeutung eines mutierten Östrogenrezeptors Abstraktband der 49. Tagung der Deutschen Gesellschaft für Gynäkologie und Geburtshilfe, S. 34, 1992

  25. Terenius, L.: Antiestrogens and breast cancer Eur. J. Cancer 7, 57, 1971

    CAS  PubMed  Google Scholar 

  26. Trams, G., Maass, H.: Specific binding of estradiol and dihydrotestosterone in human mammary cancers Cancer Res. 37, 258, 1977

    CAS  PubMed  Google Scholar 

  27. Van der Berg, H.W., Leahey, W.J., Lynch, M., Clark, R., Nelson, J.: Recombinant human interferon alpha increases oestrogen receptor expression in human breast cancer cell (ZR-75-1) and sensitizes them to the anti-proliferative effects to tamoxifen Brit.J. Cancer 55, 255, 1987

    PubMed  Google Scholar 

  28. Weimann,E., Kiess,W.: Wachstumsfaktoren — Grundlagen, Biochemie und klinische Bedeutung Schattauer Verlag Stuttgart, 1991

  29. Würz,H., Schulz,K.-D., Citoler,P., Kaiser,R.: Verteilung von Östrogen-, Gestagen-, Androgen-und Kortikosteroid-Rezeptoren in Mammakarzinomen In: Jonat,W., Maass,H. (eds): Steroidhormonrezeptoren im Karzinomgewebe Enke Verlag Atuttgart, 1982

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Schulz, K.D., Hackenberg, R., Hofmann, J. et al. Hormon- und Zytokinrezeptoren im Tumorgewebe — Therapeutische Entscheidungshilfen oder Fiktion?. Arch Gynecol Obstet 254, 668–675 (1993). https://doi.org/10.1007/BF02266140

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02266140

Navigation