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Neuro- and psychopharmacological investigation of the alkaloids convolvine and atropine

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Abstract

It has been established that convolvine blocks the M-receptors of the heart and intestine but raises the sensitivity of the M-receptors of the salivary gland and of the CNS, while atropine blocks all the abovementioned M-receptors. Convolvine has revealed characteristics of a sedative and nootropic agent. Atropine, however, which is known as a psychomotor stimulator, prevents the realization of a conditioned gastromotor reflex. An analysis has been made of the relationship between features of the pharmacological activities and chemical structures of convolvine and atropine.

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Authors
  1. Yu. R. Mirzaev
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  2. S. F. Aripova
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Additional information

Institute of the Chemistry of Plant Substances Academy of Sciences of the Republic of Uzbekistan, Tashkent, fax (3712) 40 64 75. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 75–78, January–February, 1998.

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Mirzaev, Y.R., Aripova, S.F. Neuro- and psychopharmacological investigation of the alkaloids convolvine and atropine. Chem Nat Compd 34, 56–58 (1998). https://doi.org/10.1007/BF02249687

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  • DOI: https://doi.org/10.1007/BF02249687

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