Summary
The nuclear cross-sectional area of the muscular fibers from a series of myocardial bridges was analyzed and compared to both the adjacent and underlying myocardial fibers. The series came from 12 hearts of children, ranging in age from 24 h to 2 years, with diverse forms of congenital heart disease, which caused left ventricular hypertrophy and had a myocardial bridge in the path of the anterior interventricular coronary artery. The cross-sectional areas of myocardial nuclei were measured for the bridging myocardial fibers, the adjacent myocardium, and the myocardial fibers underlying the bridged coronary artery. A significant statistical difference between the bridging muscular fibers and those underlying the submerged artery was observed, as well as between the bridging fibers and its adjacent ones. This finding suggests that myocardial bridges not only represent an anatomical abnormality, but probably imply different functional behavior as well.
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Angelini P, Trivellato M, Donis J, Leachman RD (1983) Myocardial bridges: A review.Progr Cardiovasc Dis 36:75–88
Edwards JC, Burnsides C, Swarm RL, Lansing AI (1956) Arteriosclerosis in the intramural and extramural portions of coronary arteries in the human heart.Circulation 13, 235–241
Estes EH, Entman ML, Dixon HB, Hackel DB (1966) The vascular supply of the left ventricular wall. Anatomic observations, plus a hypothesis regarding acute events in coronary artery disease.Am Heart J 71:58–65
Faruqui AMA, Maloy WC, Felner JM, Schlant RC, Logan WD, Symbas P (1978) Symptomatic myocardial bridging of coronary artery.Am J Cardiol 41:1305–1310
Ferrans VJ, Morrow AG, Roberts WC (1972) Myocardial ultrastructure in idiopathic hypertrophyc subaortic stenosis.Circulation 45:769–792
Geiringer E (1951) The mural coronary.Am Heart J 41:359–368
Hadziselimovic H (1982)Blood vessels of the human heart. VEB Georg Thieme, Leipzig, pp 38–50
Hill RC, Chitwood WR, Bashore TM, Sink JD, Cox JL, Wechsler AS (1981) Coronary flow and regional function before and after supraarterial myotomy for myocardial bridging.Ann Thorac Surg 31:176–181
Hutchins GM, Bulkley BH, Ridolfi RL, Griffith LSC, Lohr FT, Piasio MA (1977) Correlation of coronary arteriograms and left ventriculograms with postmortem studies.Circulation 56:32–37
Ishimori T, Raizner AE, Chahine RA, Awdeh M, Luchi RJ (1977) Myocardial bridges in man: Angiographic accentuation with nitroglycerine.Cathet Cardiovasc Diagn 3:59–65
Kirk ES, Honing CR (1964) Nonuniform distribution of blood flow and gradients of oxyen tension within the heart.Am J Physiol 207:351–358
Kitazume H, Kramer JR, Krauthamer D, El Tobgi S, Proudfit WL, Mason Sones F (1983) Myocardial bridges in obstructive hypertrophic cardiomyopathy.Am Heart J 106: 131–135
Mays AE, McHale PA, Greenfield JC (1981) Transmural myocardial blood flow in a canine model of coronary artery bridging.Circ Res 49:726–732
Morales AR, Romanelli R, Boucek RJ (1980) The mural left anterior descending coronary artery, strenuous exercise and sudden death.Circulation 62:230–237
Noble J, Bourassa MG, Petitclerc R, Dyrda I (1976) Myocardial bridging and milking effect of the left anterior descending coronary artery: Normal variant or obstruction?Am J Cardiol 37:993–999
Polàcek P (1961) Relation of myocardial bridges and loops on the coronary arteries to coronary occlusions.Am Heart J 61:44–52
Reig J, Loncán MP, Martín S, Binia M, Petit M, Domenech JM (1986) Ponts myocardiques—Incidence et relation avec certaines variables coronariennes.Arch Anat Histol Embryol 69:101–110
Sandritter W, Thomas C (1978)Histopathologie, 7th edn. F.K. Schattauer Verlag, Stuttgart, pp 36–42
White CW, Wright CB, Doty DB, Hiratza LF, Eastham CL, Harrison DG, Marcus ML (1984) Does visual interpretation of the coronary arteriogram predict the physiologic importance of a coronary stenosis?N Engl J Med 310:819–824
Wiggers CJ, Cotton FS (1933) The coronary pressure pulses and their interpretation.Am J Physiol 106:9–17
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Reig, J., Ruiz de Miguel, C. & Moragas, A. Morphometric analysis of myocardial bridges in children with ventricular hypertrophy. Pediatr Cardiol 11, 186–190 (1990). https://doi.org/10.1007/BF02238364
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DOI: https://doi.org/10.1007/BF02238364