Summary
The fertilization ratio of mouse ova in vitro decreased when glucose concentration in the medium was lowered. However, the addition of phloretin-2′-β-D-glucose (phloridzin), known as a glucose uptake inhibitor, restored the fertilization ratio back to the control level. The glucose moiety of the phloridzin seemed to be responsible for this effect.
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Okabe, M., Adachi, T., Kohama, Y. et al. Effect of glucose and phloretin-2′-β-D-glucose (phloridzin) on in vitro fertilization of mouse ova. Experientia 42, 398–399 (1986). https://doi.org/10.1007/BF02118625
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DOI: https://doi.org/10.1007/BF02118625