Summary
All 91,823 children born in 1980 in Bohemia (population 6.314 million; area 52,478 square kilometers) were examined at least four times during infancy and at the age of three and four years. All children who died were autopsied and those with heart disease were selected. A total of 779 children (8.223/1000 live births) were suspected by provincial pediatric cardiologists of having a heart disease. All of these were examined at the age of four years at our Center of Pediatric Cardiology. At this age heart disease was proved in 613 alive or decreased children (6.676/1000 live births), congenital cardiac malformations in 589 (6.415/1000 live births), and cardiomyopathies in 24. The most frequent congenital heart defects (CHD) were ventricular septal defect (VSD) (31.41%), atrial septal defect (ASD) (11.37%), aortic stenosis (AS) (7.64%), pulmonary stenosis (PS) (7.13%), coarctation of the aorta (CoA) (5.77%), and transposition of the great arteries (TGA) (5.43%), followed by persistent ductus arteriosus (PDA) (4.75%), atrioventricular septal defect (AVSD) and hypoplastic left heart syndrome (HLHS) (4.07% each), tetralogy of Fallot (TF) (3.56%), and pulmonary atresia (PA) (2.38%). A prevalence of less than 0.1/1000 live births was found for the remaining cardiovascular defects.
One hundred fifty-nine (25.9%) patients were admitted to our highly specialized center, 116 (19.7%) catheterized and 85 (13.9%) treated surgically, during the first four years of life. A total of 440 (71.8%) patients survived the fourth year of life. The percentage of deaths was 25.6% among those with congenital heart diseases and 71% with cardiomyopathies. The overall mortality rate was 27% in surgically and 26% in medically treated patients.
Similar content being viewed by others
References
Bierman IM, Siegel E, French FE (1965) Analysis of the outcome of all pregnancies in a community: Kanai pregnancy study.Am J Obstet Gynecol 91:37
Bound JP, Logan WFWE (1977) Incidence of congenital heart disease in Blackpool 1957–1971.Br Heart J 39:445
Carlgren LE (1959) Incidence of congenital heart disease in children born in Gothenburg 1941–1950.Br Heart J 21:40
Dickinson DF, Arnold R, Wilkinson JL (1981) Congenital heart disease among 160,480 liveborn children in Liverpool 1960–1969.Br Heart J 46:55
Ellison RC (1981) Epidemiologic contributions to the aetiology and prevention of congenital heart disease. In: Godman MJ (ed)Pediatric Cardiology, vol 4. Churchill Livingstone, Edinburgh, p 6
Feldt KH, Avasthey P, Yoshimasu F, Kurland LT, Titus JL (1971) Incidence of congenital heart disease in children born to residents of Olmstead Country, Minnesota 1950–1969.Mayo Clin Proc 46:794
Neel JV (1958) Study of major congenital defects in Japanese infants.Am J Hum Genet 10:398
Pleydel MJ (1960) Anencephaly and other congenital abnormalities: epidemiological study in Northamptonshire.Br Med J 1:309
Renwick DHG, Miller JR, Peterson D (1964) Estimates of incidence and prevalence of mongolism and of congenital heart disease in British Columbia.Can Med Assoc J 9:365
Richards MR, Merrits KK, Samuel MH (1955) Congenital malformations of the cardiovascular system in a series of 6503 infants.Pediatrics 15:12
Rose V, Boyd ARJ, Ashton TE (1964) Incidence of heart disease in children in the city of Toronto.Can Med Assoc J 91:95
Šamánek M (1981) Care of children with cardiovascular disease in Czechoslovakia.Cor Vasa 23:1
Šamánek M (1986) Results of first years of centralized care for children suffering from heart disease. In: Doyle EF, Engle MA, Gersony WM, Rashkin WJ, Talner NS (eds)Pediatric Cardiology. Springer-Verlag, New York, p 1153
Šamánek M (1989) Survival of children born with congenital heart disease.Pediatr Cardio (in press)
Šamánek M, Goetzová J, Benešová D (1986) Causes of death in neonates born with a heart malformation.Int J Cardiol 11:63
Wallooppillai NJ, Jayasinghe M de S (1970) Congenital heart disease in Ceylon.Br Heart J 32:304
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Šamánek, M., Slavík, Z., Zbořilová, B. et al. Prevalence, treatment, and outcome of heart disease in live-born children: A prospective analysis of 91,823 live-born children. Pediatr Cardiol 10, 205–211 (1989). https://doi.org/10.1007/BF02083294
Issue Date:
DOI: https://doi.org/10.1007/BF02083294