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Speciation and antibiotic susceptibility patterns of coagulase-negative staphylococci

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Abstract

During a six month period, 191 isolates of coagulase-negative staphylococci from blood, urine, cerebrospinal fluid and heart valves were identified to species level and tested for antimicrobial susceptibility. Seventy-one percent of isolates wereStaphylococcus epidermidis, 8 %Staphylococcus warneri, 7 %Staphylococcus hominis, 7 %Staphylococcus haemolyticus, 4 %Staphylococcus capitis, 2 %Staphylococcus saprophyticus and 1 %Staphylococcus cohnii. Approximately 4 % of isolates were felt to be associated with infection. Overall, 18% of isolates were susceptible to penicillin G, 61 % oxacillin, 98 % cephalothin, 98 % cefamandole, 72 % cefotaxime, 95 % cefsulodin, 76 % gentamicin, 64 % clindamycin and 98 % rifampicin. All isolates were susceptible to vancomycin. Vancomycin, rifampicin, cephalothin and cefamandole showed excellent activity against oxacillin-resistant isolates. With one exception, speciation was not helpful in determining whether or not an isolate was associated with infection.

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Authors and Affiliations

  1. Sections of Infectious Disease and Clinical Microbiology, Rush-Presbyterian-St. Luke's Medical Center, 1753 West Congress Parkway, 60612, Chicago, Illinois, USA

    D. J. Smith, R. L. Kaplan, W. Landau & G. M. Trenholme

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  1. D. J. Smith
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  2. R. L. Kaplan
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  3. W. Landau
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  4. G. M. Trenholme
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Smith, D.J., Kaplan, R.L., Landau, W. et al. Speciation and antibiotic susceptibility patterns of coagulase-negative staphylococci. Eur. J, Clin. Microbiol. 1, 228–232 (1982). https://doi.org/10.1007/BF02019713

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