Conclusion
(1) Total histamine levels were about 18 mcg of histamine base per gram of fresh human lung tissue. (2) When histamine release induced by anti-IgE serum increased, total histamine always increased. (3) Lung mast cells of all patients released histamine when challenged with anti-IgE serum. There was no difference between allergic and non-allergic subjects.
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Grant of INSERM (24.1.024.3).
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Burtin, C., Lebel, B. & Soubrane, C. Total histamine level and histamine release byn-octylamine and by anti-IgE serum in human lungs. Agents and Actions 7, 107 (1977). https://doi.org/10.1007/BF01964893
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DOI: https://doi.org/10.1007/BF01964893