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Studies on the modulation of the desensitization of the pituitary gland by luteinizing hormone-releasing hormone in the ovariectomized rat

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Summary

In ovariectomized rats the desensitization of the LH cells in vivo, which develops during constant rate infusion of LHRH, 1) does not depend on a concomitant depletion of the pituitary LH stores, 2) proceeds normally when the hypothalamo-pituitary connection has been severed and 3) is a process in which LH itself is not involved.

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Authors and Affiliations

  1. Division of Reproductive Biology, Dept of Obstetrics and Gynecology, Groningen University Hospital, 59 Oostersingel, NL-9713 EZ, Groningen, The Netherlands

    T. R. Koiter, G. C. J. van der Schaaf-Verdonk, S. Broers, N. Pols-Valkhof & G. A. Schuiling

  2. Dept of Pharmacology, Sylvius Laboratories, 72 Wassenaarseweg, NL-2333 AL, Leyden, The Netherlands

    T. R. Koiter, G. C. J. van der Schaaf-Verdonk, S. Broers, N. Pols-Valkhof & G. A. Schuiling

Authors
  1. T. R. Koiter
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  2. G. C. J. van der Schaaf-Verdonk
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  3. S. Broers
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  4. N. Pols-Valkhof
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  5. G. A. Schuiling
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Koiter, T.R., van der Schaaf-Verdonk, G.C.J., Broers, S. et al. Studies on the modulation of the desensitization of the pituitary gland by luteinizing hormone-releasing hormone in the ovariectomized rat. Experientia 42, 304–307 (1986). https://doi.org/10.1007/BF01942515

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  • DOI: https://doi.org/10.1007/BF01942515

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