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Central effect of 5,8,11,14-eicosatetraenoic acid (arachidonic acid) on the temperature in the conscious rabbit

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Summary

Hyperthermia induced by arachidonic acid in rabbit was attenuated by phenoxybenzamine, cyproheptadine and indomethacin. The reduction in arachidonic acid hyperthermia, after 6-OH-DA and the failure of PCPA to reduce this rise, indicates the involvement of noradrenaline in arachidonic acid hyperthermia.

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Authors and Affiliations

  1. Department of Pharmacology, School of Pharmacy, University of Benin, Benin City, Nigeria

    S. B. Kandasamy

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  1. S. B. Kandasamy
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Kandasamy, S.B. Central effect of 5,8,11,14-eicosatetraenoic acid (arachidonic acid) on the temperature in the conscious rabbit. Experientia 33, 1626–1627 (1977). https://doi.org/10.1007/BF01934038

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  • DOI: https://doi.org/10.1007/BF01934038

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