Summary
A primitive tumour of the pineal region in a 9 month-old boy caused hydrocephalus, ataxic gait and paraplegia leading to death after 9 months of evolution.
Histological and histochemical examination revealed a pinealoblastoma with melanotic cells as well as cartilaginous formations. The leptomeningeal seeding of the tumour showed neuroblastic and neuronal differentiation. A diagnosis of pineoblastoma with neuroepithelial and ectomesenchymal differentiation was made. This tumour belongs to a recently defined category of pineal tumours, called pineal anlage tumours.
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Mc Grogan, G., Rivel, J., Vital, C. et al. A pineal tumour with features of “Pineal anlage tumour”. Acta neurochir 117, 73–77 (1992). https://doi.org/10.1007/BF01400641
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DOI: https://doi.org/10.1007/BF01400641