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VP4 relationships between porcine and other rotavirus serotypes

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Summary

VP4 relationships of Australian porcine rotaviruses were identified using genetic reassortants and MAbs. All porcine virus isolates except BEN-144 appeared to share VP4 antigenicity with OSU virus. VP4 of BEN-144 virus (Gottfried-like virus) showed some antigenic relationships with the human neonatal viruses ST-3 and RV-3. In addition, VP4 of porcine CRW-8 showed antigenic relationships with simian SA-11, RRV and also canine K9 viruses, while that of porcine TFR-41 showed at least one way VP4 antigenic relatedness with UK bovine rotavirus. Furthermore, BMI-1 virus which is antigenically similar to an American virus SB1-A (a naturally occurring reassortant) may have arisen similarly by gene reassortment in nature in Australia.

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  1. H. S. Nagesha

    Present address: School of Veterinary Science, University of Melbourne, Parkville, Victoria, Australia

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  1. School of Microbiology, University of Melbourne, Parkville, Victoria, Australia

    H. S. Nagesha & I. H. Holmes

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  1. H. S. Nagesha
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  2. I. H. Holmes
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Nagesha, H.S., Holmes, I.H. VP4 relationships between porcine and other rotavirus serotypes. Archives of Virology 116, 107–118 (1991). https://doi.org/10.1007/BF01319235

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