References
Fentiman IS, Thomas BS, Balkwill FR, Rubens RD, Hayward JL: Primary hypothyroidism associated with interferon therapy of breast cancer. Lancet 1:1166, 1985
Burman P, Totterman TH, Oberg K, Karlsson FA: Thyroid autoimmunity in patients on long term therapy with leukocyte-derived interferon. J Clin Endocrinol Metab 63:1086–1090, 1986
Fentiman IS, Balkwill FR, Thomas BS, Russel MJ, Todd I, Bottazzo GF: An autoimmune aetiology for hypothyroidism following interferon treatment for breast cancer. Eur J Cancer Clin Oncol 24:1299–1303, 1988
Schultz M, Muller R, Von zur Muhlan A, Brabant G: Induction of hyperthyroidism by interferon-alpha. Lancet 1:1452, 1989
Mayet WJ, Hess G, Gerken G, Rossol S, Voth R, Manns M, Büschenfelde KM: Treatment of chronic type B hepatitis with recombinant alpha-interferon induces autoantibodies not specific for autoimmune chronic hepatitis. Hepatology 10:24–29, 1989
Hanafusa T, Pujol-Borrel R, Chiovato L, Russell RCG, Doniach D, Bottazzo GF: Aberrant expression of HLA-DR antigen in thyrocytes in Graves' disease: Relevance for autoimmunity. Lancet 2:1111–1115, 1983
Jansson R, Karlsson FA, Forsum W: Intrathyroidal HLA-DR expression and T lymphocyte phenotypes and nodular colloid goitre. Clin Exp Immunol 58:264–272, 1984
Davies TF, Piccinini LA: Intrathyroidal MHC class II antigen expression and thyroid autoimmunity. Endocrinol Metab Clin North Am 16(2):247–268, 1987
Buller RML, Holmes KL, Hugin A, Frederickson TN, Morse HC 3d: Induction of cytotoxic T cell responsesin vivo in the absence of CD4 helper cells. Nature 328:77–79, 1987
Korber B, Mermod N, Hood L, Stroynowski I: Regulation of gene expressions by interferons: Control of H-2 promoter responses. Science 239:1302–1306, 1988
Atkins MB, Mier JW, Parkinson DR, Gould JA, Berkman EM, Kaplan MM: Hypothyroidism after treatment with interleukin-2 and lymphokine-activated killer cells. N Engl J Med 318:1557–1563, 1988
Vargas MT, Briones-Urbina R, Gladman D, Papsin FR, Walfish PG: Antithyroid microsomal autoantibodies and HLA-DR5 are associated with thyroid dysfunction: Evidence supporting an autoimmune pathogenesis. J clin Endocrinol Metab 67:327–333, 1988
Badenhoop K, Schwartz G, Walfish PG, Drummond V, Usadel KH, Bottazzo GF: Susceptibility to thyroid autoimmune disease: Molecular analysis of HLA-D region genes identifies new markers for goitrous Hashmimoto's thyroiditis. J Clin Endocrinol Metab 71:1131–1137, 1990
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Berris, B., Feinman, S.V. Thyroid dysfunction and liver injury following alpha-interferon treatment of chronic viral hepatitis. Digest Dis Sci 36, 1657–1660 (1991). https://doi.org/10.1007/BF01296413
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DOI: https://doi.org/10.1007/BF01296413