Abstract
The incomplete understanding of drug effects at the time of marketing has led to ongoing epidemiological monitoring. The Danish National Health Service covers part of the expenses for most kinds of prescription drugs. The accounting system within the pharmacies is increasingly computerized. In 1992 we found that 96% of the pharmacies were computerized. The computerized accounting systems give no information about adverse drug effects, but this can be obtained from the Danish Hospital Register by cross-checking registries, and in some cases from the register of birth and the register of congenital malformation. There is a great need for new data sources in pharmacoepidemiology. In spite of some evident methodological problems, the Danish data sources probably have high validity compared with international sources, since they are population based.
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References
Spitzer, W.O., Drugs as determinants of health and disease in the population.J. Clin. Epidemiol. 44:823–828, 1991.
Jick, H., Walker, A.M., and Spriet-Pourra, C., Postmarketing followup.JAMA 242:2310–2314, 1979.
Hallas, J., Worm, J., Beck-Nielsen, J., Gram, L.F., Grodum, E., Damsbo, N.,et al., Drug related evants and drug utilization in patients admitted to a geriatric department.Dan. Med. Bull. 38:417–420, 1991.
Strom, B.L., and Tugwell, P., Pharmacoepidemiology: current status, prospects, and problems.Ann. Intern. Med. 113:179–181, 1990.
Ray, W.A., and Griffin, M.R., Use of Medicaid data for pharmacoepidemiology.Am. J. Epidemiol. 129:837–849, 1989.
Jick, H., Use of automated data bases to study drug effects after marketing.Pharmacotherapy 5:278–279. 1985.
Jick, H., Jick, S.S., and Derby, L., Validation of information recorded on general practitioner based computerized data resource in the United Kingdom.BMJ 302:766–768, 1991.
Sørensen, H.T., Compendium in public health data sources.Am. J. Epidemiol. 135:325–326, 1992.
MEFA. Tal og data 1991.Medicin og sundhedsvœsen. Copenhagen: MEFA, 1991.
Faich, G.A. Adverse-drug-reaction reporting.N. Engl. J. Med. 314:1589–1592, 1986.
Kramer, M.S. Clinical Epidemiology and Biostatistics. Berlin: Springer-Verlag, 1988.
Meulengracht, A., and Madsen, M.,Registre indenfor sundhedsområdet. Copenhagen: DIKE, 1982.
Jick, H., Use of hospital discharge diagnosis in case-control studies.Am. J. Public Health 74:730, 1984.
Sørensen, H.T., Nielsen, F.E., Klausen, I.C., and Petersen, J., The relationship between serum enzyme activity, infarct site, and cardiac complications after a first myocardial infarction.Scand. J. Prim. Health Care 7:93–97, 1989.
Loft, A., Andersen, T.F., Brønnum-Hansen, H., Roepstorff, C., and Madsen, M. Early postoperative mortality following hysterectomy. A Danish population based study.Br. J. Obstet. Gynaecol. 98:147–154, 1991.
Devantier, A., Kjer, J.J., Landspatientregistret-et forskningsredskab?.Ugeskr Lœger 153:516–517, 1991.
Sørensen, H.T., Nielsen, B., and Nielsen, J.Ø., Anaphylactic shock occurring outside hospitals.Allergy 44:288–290, 1989.
rosholm, J.-U., Hallas, J., and Gram, L.F., Outpatient utilization of antidepressants: A prescription database analysis.J. Affect Dis. 27:21–28, 1993.
Hallas, J., Hansen, N-C.G., Individual utilization of anti-asthma medication by young adults; A prescription database analysis. In press.
Larsen, B.O. If quality assurance/peer review as the ‘main course’, feedback could be the ‘appetizer.’ Pharmaceutisch Weekblad Scientific Edition 13 (suppl F): 9, 1991.
Christensen, B., Sørensen, H.T., and Mabeck, C.E., Referral from general practice to dermatologists.Scand. J. Prim. Health Care 6:29–32, 1988.
Sørensen, H.T., Christensen, B., and Mabeck, C.E. Are GP referrals influenced by the availability of consultants?Br. Med. J. 297:1196, 1988.
Christensen, B., Sørensen, H.T., and Mabeck, C.E. Differences in referral rate from general practice.Fam. Pract. 6:19–22, 1989.
Sørensen, H.T., Ejlersen, E., Møller-Petersen, J., Rasmussen, H.H., and Olesen, F. General practitioners' awareness of colorectal cancer.Br. Med. J. 301:445–446, 1990.
Sørensen, H.T., Ejlersen, E., Møller-Petersen, J., Rasmussen, H.H., and Olesen, F., Overall use of proctoscopy in general practice and possible relation to the stage of rectal cancer.Fam. Pract. 9:145–148, 1992.
Sørensen, H.T., Ejlersen, E., Rasmussen, H.H., Møller-Petersen, J., and Olesen, F., Thrombolytic treatment of acute myocardial infarction in general practice: need for evaluation.Quality Health Care 1:140, 1992.
Kyrsgård, B., Lynge, E., and Olsen, J.,Registerforskning Det Etiske Råd, Copenhagen, 1991.
Sørensen, H.T., Farmakologisk epidemiologi.Ugeskr Lœger 155:207, 1993.
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Sørensen, H.T., Larsen, B.O. A population-based Danish data resource with possible high validity in pharmacoepidemiological research. J Med Syst 18, 33–38 (1994). https://doi.org/10.1007/BF00999322
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DOI: https://doi.org/10.1007/BF00999322