Summary
Oxyfedrine has cardiostimulant effects due to direct activation of beta-receptors. It is devoid of stimulant effects on beta-receptors of vascular and nonvascular smooth muscle. However, oxyfedrine relaxes smooth muscle by a papaverine-like mechanism.
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Part of the results was presented to the 1st Meeting of the Portuguese Pharmacological Society (Oeiras, October, 1970). This work was supported by a grant from the Institute) de Alta Cultura.
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Osswald, W., Guimarães, S. Cardioselective betareceptor stimulant properties of oxyfedrine. Naunyn-Schmiedebergs Arch. Pharmak. 270, 203–209 (1971). https://doi.org/10.1007/BF00997090
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DOI: https://doi.org/10.1007/BF00997090