Conclusions
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1.
Hydrogenation of α-nitrpcaprolactam by treatment with a Pd catalyst in the presence of S-α-phenylethylamine in aprotic solvents proceeds via azoxycaprolactam as an intermediate.
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2.
The asymmetric effect in the enantioselecive hydrogenation of nitrocaprolactam on a chiral Pd catalyst occurs at the stage where azoxycaprolactam is reduced.
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Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 6, pp. 1371–1375, June, 1988.
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Gogoladze, D.D., Levitina, E.S., Godunova, L.F. et al. Mechanism for enantioselective hydrogenation of α-nitrocaprolactam on a chiral palladium catalyst. Russ Chem Bull 37, 1207–1210 (1988). https://doi.org/10.1007/BF00961932
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DOI: https://doi.org/10.1007/BF00961932