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Indole derivatives

XCII. Alkylation of barbituric acids with mannich bases

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

5-Substituted (butyl, phenyl)-5-skatyl(5-methoxyskatyl)barbituric acids were obtained by alkylation of the corresponding barbituric acids with gramine and 5-methoxygramine in dimethylformamide and dimethyl sulfoxide. 5,5-Dialkylation products were obtained in the alkylation of barbituric and thiobarbituric acids with gramine.

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Literature cited

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Authors and Affiliations

  1. D. I. Mendeleeva Moscow Institute of Chemical Technology, USSR

    N. N. Suvorov, V. S. Velezheva, V. V. Vampilova & E. N. Gordeev

Authors
  1. N. N. Suvorov
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  2. V. S. Velezheva
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  3. V. V. Vampilova
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  4. E. N. Gordeev
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Additional information

See [1] for communication XCI.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 515–518, April, 1974.

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Suvorov, N.N., Velezheva, V.S., Vampilova, V.V. et al. Indole derivatives. Chem Heterocycl Compd 10, 447–449 (1974). https://doi.org/10.1007/BF00945637

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  • DOI: https://doi.org/10.1007/BF00945637

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