Abstract
Cronkhite-Canada syndrome is generally accepted as being a benign disorder. We herein present a 66-year-old-male patient with Cronkhite-Canada syndrome who had a carcinoma of the sigmoid colon along with multiple colonic polyps, which included juvenile-type polyps, adenomas, and hyperplastic polyps. In the world literature, there have been 34 cases of Cronkhite-Canada syndrome associated with colorectal carcinoma among the 280 reported cases of this syndrome. This report thus adds to the growing evidence that Cronkhite-Canada syndrome may be a premalignant condition for colorectal carcinoma. A periodic examination of the colon is therefore advised in order to detect any development of colorectal carcinoma at an early stage.
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Nakatsubo, N., Wakasa, R., Kiyosaki, K. et al. Cronkhite-Canada syndrome associated with carcinoma of the sigmoid colon: Report of a case. Surg Today 27, 345–348 (1997). https://doi.org/10.1007/BF00941810
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DOI: https://doi.org/10.1007/BF00941810