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Synthesen neuer Chinolon-Chemotherapeutika, 1. Mitt.: Pyridochinoline und Pyridophenanthroline als “lin-benzo-Nalidixinsäure”-Derivate

Syntheses of novel quinolone-chemotherapeutics, I: Pyridoquinolines and pyridophenanthrolines as derivatives of “lin-benzo-nalidixic acid”

  • Organische Chemie Und Biochemie
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Abstract

Expansion of nalidixic acid (NA) has been accomplished by linear insertion of a benzo-ring between the two pyrido moieties. The resulting compounds exhibit antibacterial activity comparable toNA and are highly fluorescent. The regioselective hydrogenation of 1,7-phenanthrolines was studied.

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Authors and Affiliations

  1. Institut für Organische Chemie, Technische Universität Wien, A-1060, Wien, Österreich

    U. Jordis, F. Sauter & M. Rudolf

  2. South China Institute of Technology, Guangzhou (Canton), The People's Republic of China

    Gan Cai

Authors
  1. U. Jordis
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  2. F. Sauter
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  3. M. Rudolf
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  4. Gan Cai
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Jordis, U., Sauter, F., Rudolf, M. et al. Synthesen neuer Chinolon-Chemotherapeutika, 1. Mitt.: Pyridochinoline und Pyridophenanthroline als “lin-benzo-Nalidixinsäure”-Derivate. Monatsh Chem 119, 761–780 (1988). https://doi.org/10.1007/BF00809690

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  • DOI: https://doi.org/10.1007/BF00809690

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