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Synthesis and reactions of 2-mercaptomethyl-1,3,4-oxadiazolin-5-one

Synthese und Reaktionen von 2-Mercaptomethyl-1,3,4-oxadiazolin-5-on

  • Organische Chemie Und Biochemie
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Summary

The title compound (4) was synthesized from thioglycolic acid hydrazide and ethyl chloroformate. The reactions of4 with aromatic amines, amino derivatives, hydrazine hydrate, hydroxylamine, and formamide were studied. Addition of compound4 to α,β-unsaturated compounds,i.e. chalcones, maleic anhydride, quinones, and acrylonitrile, was investigated.

Zusammenfassung

Die Titelverbindung (4) wurde aus Thioglycolsäurehydrazid und Chlorameisensäureethylester hergestellt. Die Reaktionen von4 mit aromatischen Aminen, Aminoderivaten, Hydrazinhydrat, Hydroxylamin und Formamid sowie die Addition von4 an α,β-ungesättigte Verbindungen (Chalkone, Maleinsäureanhydrid, Chinone, Acetonitril) wurden untersucht.

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Authors and Affiliations

  1. Chemistry Department, Faculty of Science, Zagazig University, Zagazig, Egypt

    M. M. Hamad, S. A. Said & Y. M. El-Ekyabi

Authors
  1. M. M. Hamad
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  2. S. A. Said
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  3. Y. M. El-Ekyabi
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Hamad, M.M., Said, S.A. & El-Ekyabi, Y.M. Synthesis and reactions of 2-mercaptomethyl-1,3,4-oxadiazolin-5-one. Monatsh Chem 127, 549–555 (1996). https://doi.org/10.1007/BF00807080

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  • DOI: https://doi.org/10.1007/BF00807080

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