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Synthesis of amino-substituted 2-methylcoumarins, chromans, and benzoxepanes and their N-(alkylaminoacyl) derivatives

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The isomeric compositions of the products of nitration of 2-methylcoumaran and chroman with acetyl nitrate were determined. More convenient methods for the synthesis of 7-amino-2-methylcoumaran and 8-aminochroman were developed, and 9-amino-1-benzoxepane was obtained for the first time. Alkylaminoacylamino-substituted 2-methylcoumarans, chromans, and 1-benzoxepanes were synthesized. A method for the synthesis of 2-bromocaproyl chloride from caproic acid was developed.

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Authors and Affiliations

  1. V. Kapsukas Vilnius State University, 232734, Vilnius

    V. K. Daukshas, O. Yu. Pyatrauskas & G. V. Purvanyatskas

Authors
  1. V. K. Daukshas
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  2. O. Yu. Pyatrauskas
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  3. G. V. Purvanyatskas
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 320–324, March, 1987.

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Daukshas, V.K., Pyatrauskas, O.Y. & Purvanyatskas, G.V. Synthesis of amino-substituted 2-methylcoumarins, chromans, and benzoxepanes and their N-(alkylaminoacyl) derivatives. Chem Heterocycl Compd 23, 266–270 (1987). https://doi.org/10.1007/BF00761981

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  • DOI: https://doi.org/10.1007/BF00761981

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