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Advances in the synthesis of cardenolides

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Chemistry of Natural Compounds Aims and scope

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Literature cited

  1. L. Fieser and M. Fieser, Steroids, Reinhold, New York (1959).

    Google Scholar 

  2. N. K. Abubakirov, Khim. Prirodn. Soedin., 553 (1971).

  3. I. F. Makarevich, É. P. Kemertelidze, S. G. Kislichenko, V. V. Zatula, A. A. Resnichenko, D. G. Kolesnikov, and I. P. Kovalev, Cardenolides and Bufadienolides [in Russian], Tbilisi (1975).

  4. F. Sondheimer, Chem. Britain,1, 454 (1965).

    Google Scholar 

  5. R. Deghenghi, Pure Appl. Chem.,21, 153 (1970).

    Google Scholar 

  6. S. I. Kanveskaya and O. S. Madaeva, Usp. Khim.,15, 177 (1946).

    Google Scholar 

  7. R. B. Turner, Chem. Rev.,43, 1 (1948).

    Google Scholar 

  8. M. Rubin, W. D. Paist, and R. C. Elderfield, J. Org. Chem.,6, 260 (1941).

    Google Scholar 

  9. R. C. Linville and R. C. Elderfield, J. Org. Chem.,6, 270 (1941).

    Google Scholar 

  10. W. S. Knowless, J. A. Kuck, and R. C. Elderfield, J. Org. Chem.,7, 347 (1942).

    Google Scholar 

  11. E. R. Marshall, J. A. Kuck, and R. C. Elderfield, J. Org. Chem.,7, 444 (1942).

    Google Scholar 

  12. J. Fried, R. G. Linville, and R. C. Elderfield, J. Org. Chem.,7, 362 (1942).

    Google Scholar 

  13. W. S. Knowless, J. Fried, and R. C. Elderfield, J. Org. Chem.,7, 383 (1942).

    Google Scholar 

  14. L. Ruzicka, T. Reichstein, and A. Furst, Helv. Chim. Acta,24, 76 (1941).

    Google Scholar 

  15. L. Ruzicka, P. A. Plattner, and A. Furst, Helv. Chim. Acta,24, 761 (1941).

    Google Scholar 

  16. L. Ruzicka, P. A. Plattner, and A. Furst, Helv. Chim. Acta,25, 79 (1942).

    Google Scholar 

  17. I. van P. Tarrey, J. A. Kuck, and R. C. Elderfield, J. Org. Chem.,6, 289 (1942).

    Google Scholar 

  18. L. Ruzicka, P. A. Plattner, and J. Pataki, Helv. Chim. Acta,25, 425 (1942).

    Google Scholar 

  19. L. Ruzicka, P. A. Plattner, and G. Balla, Helv. Chim. Acta,25, 65 (1942).

    Google Scholar 

  20. L. Ruzicka, P. A. Plattner, and H. Heusser, Helv. Chim. Acta,25, 435 (1942).

    Google Scholar 

  21. P. A. Plattner, L. Ruzicka, and A. Furst, Helv. Chim. Acta,26, 2274 (1943).

    Google Scholar 

  22. L. Ruzicka, P. A. Plattner, and H. Heusser, Helv. Chem. Acta,27, 186 (1944).

    Google Scholar 

  23. L. Ruzicka, P. A. Plattner, and J. Pataki, Helv. Chim. Acta,27, 988 (1944).

    Google Scholar 

  24. P. A. Plattner, E. Hardegger, and H. Bucher, Helv. Chim. Acta,28, 167 (1945).

    Google Scholar 

  25. P. A. Plattner and A. Furst, Helv. Chim. Acta,28, 173 (1945).

    Google Scholar 

  26. L. Ruzicka, P. A. Plattner, H. Heusser, and O. Ernst, Helv. Chim. Acta,29, 248 (1946).

    Google Scholar 

  27. L. Ruzicka, P. A. Plattner, and H. Heusser, Helv. Chim. Acta,29, 473 (1946).

    Google Scholar 

  28. H. Heusser and H. Wuthier, Helv. Chim. Acta,30, 1460 (1947).

    Google Scholar 

  29. L. Ruzicka, P. A. Plattner, H. Heusser, and J. Pataki, Helv. Chim. Acta,29, 936 (1946).

    Google Scholar 

  30. P. A. Plattner, L. Ruzicka, H. Heusser, J. Pataki, and K. Meier, Helv. Chim. Acta,29, 942 (1946).

    Google Scholar 

  31. K. Meyer, Helv. Chim. Acta,29, 1580 (1946).

    Google Scholar 

  32. L. Ruzicka, P. A. Plattner, H. Heusser, and K. Meier, Helv. Chim. Acta,30, 1342 (1947).

    Google Scholar 

  33. N. Danieli, Y. Mazur, and F. Sondheimer, J. Am. Chem. Soc.,84, 875 (1962).

    Google Scholar 

  34. N. Danieli, Y. Mazur, and F. Sondheimer, Tetrahedron,22, 3189 (1966).

    Google Scholar 

  35. P. A. Plattner, L. Ruzicka, H. Heusser, and E. Angliker, Helv. Chim. Acta,30, 385 (1947).

    Google Scholar 

  36. P. A. Plattner, L. Ruzicka, H. Heusser, and E. Angliker, Helv. Chim. Acta,30, 395 (1947).

    Google Scholar 

  37. P. A. Plattner, L. Ruzicka, H. Heusser, and E. Angliker, Helv. Chim. Acta,30, 1073 (1947).

    Google Scholar 

  38. F. S. Khristulas, M. B. Gorovits, and N. K. Abubakirov, Dokl. Akad. Nauk SSSR,193, 1083 (1970).

    Google Scholar 

  39. F. S. Khristulas, M. B. Gorovits, and N. K. Abubakirov, Khim. Prirodn. Soedin., 545 (1970).

  40. M. Okada and Y. Saito, Steroids,6, 645 (1965).

    Google Scholar 

  41. P. A. Plattner and H. Heusser, Helv. Chim. Acta,29, 727 (1946).

    Google Scholar 

  42. M. Okada, A. Yamada, Y. Saito, and M. Hasunuma, Chem. Pharm. Bull.,14, 496 (1966).

    Google Scholar 

  43. C. R. Engel and G. Bach, Steroids,3, 593 (1964).

    Google Scholar 

  44. G. Bach, J. Capitaine, and C. R. Engel, Can. J. Chem.,46, 733 (1968).

    Google Scholar 

  45. P. A. Plattner, K. Meier, and H. Heusser, Helv. Chem. Acta,30, 905 (1947).

    Google Scholar 

  46. P. A. Plattner, H. Heusser, and A. Segre, Helv. Chim. Acta,31, 249 (1948).

    Google Scholar 

  47. H. Heusser, M. Roth, O. Rohr, and R. Anliler, Helv. Chim. Acta,38, 1178 (1955).

    Google Scholar 

  48. P. Hofer, H. Linde, and K. Meyer, Helv. Chim. Acta,45, 1041 (1962).

    Google Scholar 

  49. W. Fritsch and H. Rusching, Ann. Chem.,655, 39 (1962).

    Google Scholar 

  50. W. Fritsch, U. Stache, and H. Ruschig, Ann. Chem.,699, 195 (1966).

    Google Scholar 

  51. W. Fritsch, U. Stache, W. Haede, K. Radschit, and H. Ruschig, Ann. Chem.,721, 168 (1969).

    Google Scholar 

  52. W. Fritsch, W. Haede, K. Radscheit, U. Stache, and H. Ruschig, Ann. Chem., 621 (1974).

  53. U. Stache, W. Fritsch, W. Haede, K. Radscheit, and K. Fachinger, Ann. Chem.,726, 136 (1969).

    Google Scholar 

  54. W. Fritsch, H. Kohe, U. Stache, W. Haede, K. Radscheit, and H. Ruschig, Ann. Chem.,727, 110 (1969).

    Google Scholar 

  55. H. C. Murray and P. D. Meister, US Patent No. 2,889,255 (1959); Chem. Abstr.,53, 22098d (1959).

  56. M. Shirasaka and M. Tsuruta, Chem. Pharm. Bull.,9, 238 (1961).

    Google Scholar 

  57. Y. M. Y. Haddad, H. B. Henbest, J. Husbands, and T. R. B. Mitchell, Proc. Chem. Soc., 361 (1961).

  58. U. Valcavi and S. Innocenti, Farmaco, Ed. Sci.,29, 194 (1974).

    Google Scholar 

  59. M. E. Wall, H. E. Kenney, and E. S. Rothman, J. Am. Chem. Soc.,77, 5665 (1955).

    Google Scholar 

  60. T. A. Pkheidze and O. S. Madaeva, Khim. Prirodn. Soedin., 355 (1968).

  61. F. S. Khristulas, M. B. Gorovits, and N. K. Abubakirov, Khim. Prirodn. Soedin., 132 (1968).

  62. E. Yoshii and K. Ozaki, Chem. Pharm. Bull.,20, 1585 (1972).

    Google Scholar 

  63. E. Yoshii, T. Koizumi, H. Ikeshima, K. Ozaki, and I. Hayashi, Chem. Pharm. Bull.,23, 2496 (1975).

    Google Scholar 

  64. E. Yoshii, H. Ikeshime, and K. Ozaki, Chem. Pharm. Bull.,20, 1827 (1972).

    Google Scholar 

  65. R. Deghenghi, A. Philipp, and R. Gaudry, Tetrahedron Lett., 2045 (1963).

  66. P. D. Meister and H. C. Murray, US Patent No. 2,930,791 (1960); Chem. Abstr.,54, 17471c (1960).

  67. G. Kruger, Can. J. Chem.,52, 4139 (1974).

    Google Scholar 

  68. J. Kaldova, K. Heusler, H. Ueberwasser, G. Anner, and A. Wettstein, Helv. Chim. Acta,46, 1361 (1963).

    Google Scholar 

  69. G. Kruger and A. Verwijs, J. Org. Chem.,35, 2415 (1970).

    Google Scholar 

  70. G. Kruger, J. Org. Chem.,36, 2129 (1971).

    Google Scholar 

  71. W. Eberlein, J. Nickl, J. Heider, G. Dahms, and H. Machleidt, Chem. Ber.,105, 3686 (1972).

    Google Scholar 

  72. M. Okada and Y. Saito, Chem. Pharm. Bull.,16, 2223 (1968).

    Google Scholar 

  73. T. Shigei, H. Tsuru, Y. Saito, and M. Okada, Experientia29, 449 (1973).

    Google Scholar 

  74. R. K. Naidoo, T. R. Witty, W. A. Remers, and H. R. Besch, J. Pharm. Sci.,63, 1391 (1974).

    Google Scholar 

  75. R. Thomas, J. Boutagy, and A. Gelbart, J. Pharm. Sci.,63, 1649 (1974).

    Google Scholar 

  76. G. Wulff and G. Rohle, Angew. Chem.,86, 173 (1974).

    Google Scholar 

  77. N. Sh. Pal'yants, M. B. Gorovits, and N. K. Abubakirov, Khim. Prirodn. Soedin., 263 (1975).

  78. N. Sh. Pal'yants and N. K. Abubakirov, Khim. Prirodn. Soedin., 523 (1975).

  79. N. Sh. Pal'yants, A. F. Bochkov, and N. K. Abubakirov, Khim. Prirodn. Soedin., 58 (1975).

  80. N. Sh. Pal'yants, M. B. Gorovits, and N. K. Abubakirov, Khim. Prirodn. Soedin., 765 (1976).

  81. N. Sh. Pal'yants and N. K. Abubakirov, Khim. Prirodn. Soedin., 72 (1977).

  82. R. Petersen, H. Flasch, and N. Heinz, Arzneimittelforschung, 642 (1977).

  83. J. Thiem and H.-J. Jürgens, Chem. Ber.,110, 2852 (1977).

    Google Scholar 

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Authors
  1. M. B. Gorovits
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  2. N. K. Abubakirov
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Additional information

Institute of the Chemistry of Plant Substances, Academy of Sciences of the Uzbek SSR, Tashkent. Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 283–299, May–June, 1978.

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Gorovits, M.B., Abubakirov, N.K. Advances in the synthesis of cardenolides. Chem Nat Compd 14, 233–246 (1978). https://doi.org/10.1007/BF00713306

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  • DOI: https://doi.org/10.1007/BF00713306

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