Skip to main content
Springer Nature Link
Log in

Active transport of urea across the skin of the euryhaline toad,Bufo viridis

  • Transport Processes, Metabolism and Endocrinology; Kidney, Gastrointestinal Tract, and Exocrine Glands
  • Letters and Notes
  • Published:
Pflügers Archiv Aims and scope Submit manuscript

Abstract

Urea is accumulated in considerable amounts (>100 mM) in the blood of the euryhaline toadBufo viridis, under conditions of adaptation to high salinities. Salt adaptation increases active transport of urea (inward direction) in the skin, which was measuredin vitro. The active transport of urea is insensitive to ADH, and was inhibited nearly 50% by 0.5 mM phloretin. This transport system is different from the facilitated diffusion of urea which has been studied extensively in the toad urinary bladder, and may offer a simple model system for the study of active urea transport.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Bruus, K., Kristense, P. and Hviid Larsen, E. (1976) Pathway for chloride and sodium transport across toad skin. Acta Physiol. Scand.97, 31–47.

    Google Scholar 

  • Garcia-Romeu, F., Masoni, A. & Isaia, J. (1981) Active urea transport through the isolated skin of frogs and toads. Submitted.

  • Katz, U. (1973) Studies on the adaptation of the toadBufo viridis to high salinities: oxygen consumption, plasma concentration and water content of the tissues. J. Exp. Biol. 58:785–796.

    Google Scholar 

  • Katz, U. (1975) Salt induced changes in sodium trnasport across the skin of the euryhaline toadBufo viridis. J. Physiol. 247:537–550.

    Google Scholar 

  • Levine, S., Franki, N. & Hays, R.M. (1973) A saturable vasopressin-sensitive carrier for urea and acetamide in the toad bladder epithelial cell. J. Clin. Invest. 52:2083–2086.

    Google Scholar 

  • Tercafs, R.R., & Schoffeniels, E. (1962) Adaptation of amphibians to salt water. Life Sci. 1:19–23.

    Google Scholar 

  • Ussing, H.H. & Johansen, B. (1969) Anomalous transport of sucrose and urea in toad skin. Nephron 6:317–328.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Groupe de biologie marine du Departement de biologie du C.E.A. Station Marine, B.P. 68, 06230, Villefranche-sur-Mer, France

    U. Katz, F. Garcia-Romeu, A. Masoni & J. Isaia

  2. Department of Biology, The Technion, Haifa, Israel

    U. Katz, F. Garcia-Romeu, A. Masoni & J. Isaia

Authors
  1. U. Katz
    View author publications

    You can also search for this author inPubMed Google Scholar

  2. F. Garcia-Romeu
    View author publications

    You can also search for this author inPubMed Google Scholar

  3. A. Masoni
    View author publications

    You can also search for this author inPubMed Google Scholar

  4. J. Isaia
    View author publications

    You can also search for this author inPubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Katz, U., Garcia-Romeu, F., Masoni, A. et al. Active transport of urea across the skin of the euryhaline toad,Bufo viridis . Pflugers Arch. 390, 299–300 (1981). https://doi.org/10.1007/BF00658281

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00658281

Key words