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Cyclization reactions of nitriles. 28. Synthesis and reactions of 3β-acetoxy-2′-methyl-5′-cyanoandrost-5-eno[17,16-c]pyridine-6′ (1′H)-thione

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

3β-Acetoxy-2′-methyl-5′-cyanoandrost-5-eno[17,16-c]pyridine-6′(1′H)-thione was obtained by thiylation of 16α-dicyanomethyl-3β-hydroxypregn-5-en-20-one acetate, and its alkylation by chloroacetonitrile and phenacyl bromide was studied. The same thione was also synthesized by treating the corresponding 6′-bromo-2′-methyl-5′-cyanoandrost-5-eno[17,16-c]pyridine with urea.

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Authors and Affiliations

  1. T. G. Shevchenko Voroshilovgrad State Pedagogical Institute, 348011, Voroshilovgrad

    Yu. A. Sharanin & G. V. Klokol

Authors
  1. Yu. A. Sharanin
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  2. G. V. Klokol
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Additional information

Communication 27, see [1].

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 943–946, July, 1988.

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Sharanin, Y.A., Klokol, G.V. Cyclization reactions of nitriles. 28. Synthesis and reactions of 3β-acetoxy-2′-methyl-5′-cyanoandrost-5-eno[17,16-c]pyridine-6′ (1′H)-thione. Chem Heterocycl Compd 24, 775–778 (1988). https://doi.org/10.1007/BF00633174

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  • DOI: https://doi.org/10.1007/BF00633174

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