Skip to main content
Log in

Properties of somatic membrane patches of snail neurons under voltage clamp

  • Published:
Pflügers Archiv Aims and scope Submit manuscript

Summary

Helix pomatia ganglion cells have voltage clamp currents which are similar to those of the squid axon if short voltage clamp pulses are applied and resting membrane voltages are below 60 mV.

If voltage pulses are prolonged, there is a progressive decay of the late outward current which does not follow first order kinetics. With higher resting and holding potentials an additional subthreshold current component appears which probably is part of a pacemaker mechanism.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Alving, B. O.: Spontaneous activity of isolated Aplysia somata. J. gen. Physiol.51, 29–45 (1968).

    Google Scholar 

  • —: Differences between pacemaker and nonpacemaker neurons of Aplysia on voltage clamping. J. gen. Physiol.54, 512–531 (1969).

    Google Scholar 

  • Frank, K., Tauc, L.: Voltage clamp studies of molluscan neuron membrane properties. In: The cellular function of membrane transport. Ed. by J. Hoffmann. Englewood Cliffs: Prentice Hall, Inc. 1964.

    Google Scholar 

  • Frankenhaeuser, B., Hodgkin, A. L.: The after-effects of impulses in the giant nerve fibres of loligo. J. Physiol. (Lond.)131, 341–376 (1956).

    Google Scholar 

  • Hodgkin, A. L., Huxley, A. F.: Quantitative description of membrane current and its application to conduction and excitation in nerve. J. Physiol. (Lond.)117, 500–544 (1952).

    Google Scholar 

  • Leicht, R., Meves, H., Wellhörner, H.: Voltage-Clamp-Versuche an Riesennervenzellen der Weinbergschnecke Helix pomatia. Pflügers Arch.316, R66 (1970).

    Google Scholar 

  • Neher, E., Lux, H. D.: Voltage clamp on Helix pomatia neuronal membrane: Current measurement over a limited area of the soma surface. Pflügers Arch.311, 272–277 (1969).

    Google Scholar 

  • Stevens, Ch. F.: Voltage clamp analysis of a repetitively firing neuron. Discussion in: Basic mechanisms of the epilepsies. Ed. by H. H. Jaspers et al. Boston: Little, Brown and Co. 1969.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Neher, E., Lux, H.D. Properties of somatic membrane patches of snail neurons under voltage clamp. Pflugers Arch. 322, 35–38 (1971). https://doi.org/10.1007/BF00586662

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00586662

Key-Words

Schlüsselwörter

Navigation