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Study of the conformation of the antibiotic A-128-OP and its derivatives by the methods of optical rotatory dispersion and circular dichroism

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Summary

1. The optical rotatory dispersion and circular dichroism of the antibiotic A-128-OP and derivatives of it have been investigated in the wavelength range from 230 to 450 nm.

2. On the basis of the ORD and CD characteristics and the results of biochemical tests, it has been concluded that the molecule of the antibiotic A-128-Op has a “preferred” conformation which is most favorable for its functioning.

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Authors
  1. V. V. Romanov
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  2. I. G. Smirnova
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  3. V. E. Minaev
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  4. A. B. Silaev
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  5. G. S. Katrukha
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Additional information

M. V. Lomonosov State University. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 640–645, September–October, 1974.

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Romanov, V.V., Smirnova, I.G., Minaev, V.E. et al. Study of the conformation of the antibiotic A-128-OP and its derivatives by the methods of optical rotatory dispersion and circular dichroism. Chem Nat Compd 10, 648–651 (1974). https://doi.org/10.1007/BF00567861

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  • DOI: https://doi.org/10.1007/BF00567861

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