Abstract
3-Cyano- and 3-carbamoyl-2-chloropyridines react with hydrazine hydrate to form substituted 3-amino-1H-pyrazolo[3,4-b]pyridines and 3-oxo-2,3-dihydro-1H-pyrazolo[3,4-b]pyridines. Hydrazine hydrate reacts with 3-carbamoyl-2-chloro-5-oxo-5,7-dihydrofuro[3,4-b]pyridine to form substituted 3,5-dioxo-2,3,5,7-tetrahydro-1H-pyrazolo[3,4-b]furo[3,4-e]pyridine.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1218–1222, September, 1992.
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Kalme, Z.A., Roloff, B., Pelcher, Y.E. et al. Nucleophilic substitution reactions in 2-chloropyridines and 2,5-dioxo-1,2,5,7-tetrahydro-1H-furo[3,4-b]pyridines. Chem Heterocycl Compd 28, 1031–1035 (1992). https://doi.org/10.1007/BF00531481
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DOI: https://doi.org/10.1007/BF00531481