Summary
In these four drugs three to five polymorphic modifications each were found. All these compounds exist in the commercial products in a low temperature phase and can be transformed into high temperature modifications by heating. The investigations were carried out by means of thermomicroscopy, differential scanning calorimetry and infrared spectroscopy.
Similar content being viewed by others
Literatur
Porsche U (1988) Dissertation, Innsbruck
Kofler A (1949) Mikrochem 34:15–24
Kuhnert-Brandstätter M, Völlenklee R (1985) Fresenius Z Anal Chem 322:164–169
Kofler L, Kofler A (1954) Thermomikromethoden. Universitätsverlag Wagner, Innsbruck
Kuhnert-Brandstätter M (1971) Thermomicroscopy in the analysis of pharmaceuticals. International Series of Monographs in Analytical Chemistry, vol 45. Pergamon Press, Oxford
Kuhnert-Brandstätter M (1982) Thermomicroscopy of organic compounds. In: Wilson and Wilson's Comprehensive Analytical Chemistry, vol XVI. Elsevier, Amsterdam
Burger A, Ramberger R (1979) Mikrochim Acta 11:259–271
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Kuhnert-Brandstätter, M., Porsche, U. Thermoanalytische und IR-spektroskopische Untersuchungen an polymorphen Arzneistoffen: Amcinonid, Indalpin, Metahexamid und Moclobemid. Z. Anal. Chem. 334, 752–758 (1989). https://doi.org/10.1007/BF00491311
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00491311