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Direct hydroxylation of imidazoles

New method for the synthesis of 2-imidazolones, arylimidazolones, and perimidones

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

It is shown that the N-substituted derivatives of 4,5-diphenylimidazole, benzimidazole, naphth[1,2]imidazole, perimidine, and aceperimidine are hydroxylated by alkali metal hydroxides to give the corresponding 2-imidazolones and perimidones in high yields.

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Authors and Affiliations

  1. Rostov-on-Don State University, USSR

    I. S. Kashparov & A. F. Pozharskii

Authors
  1. I. S. Kashparov
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  2. A. F. Pozharskii
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Additional information

The material in this paper regarding the synthesis of perimidones and aceperimidones should be considered as communication V of our series entitled “Heterocyclic Analogs of Pleiadiene.“ See [16] for communication IV.

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 124–128, January, 1971.

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Kashparov, I.S., Pozharskii, A.F. Direct hydroxylation of imidazoles. Chem Heterocycl Compd 7, 116–120 (1971). https://doi.org/10.1007/BF00477965

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  • DOI: https://doi.org/10.1007/BF00477965

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