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Bromo derivatives of 4-phenyl-2,3-dihydro-1h-1,5-benzodiazepin-2-one

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Monobromo and dibromo derivatives were synthesized by bromination of 4-phenyl-2,3-dihydro-1H-1,5-benzodiazepin-2-one with bromine under various conditions and with N-bromosuccinimide in CCl4. 7-Bromo- and 8-bromo-4-phenyl-2,3-dihydro-1H-1,5-benzodiazepin-2-ones were obtained by condensation of 4-bromo-o-phenylenediamine with benzoylacetic ester in refluxing xylene. The UV and PMR spectra of the products are discussed.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 411–415, March, 1978.

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Solomko, Z.F., Avramenko, V.I. & Pribega, L.V. Bromo derivatives of 4-phenyl-2,3-dihydro-1h-1,5-benzodiazepin-2-one. Chem Heterocycl Compd 14, 340–344 (1978). https://doi.org/10.1007/BF00470573

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  • DOI: https://doi.org/10.1007/BF00470573

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