Summary
In 16 guinea pigs restricted lesions of the cochlea and the resulting degeneration in the cochlear nerve and in the cochlear nuclei were confirmed by Bodian and Schultze-Gros methods, to study the relationships of central projection of single cochlear turns with the cytoarchitectural areas of the cochlear nucleus complex. The ascending branches of the basal turn terminate in the medial part of the anteroventral cochlear nucleus (AVCN) including the globular cell area, the small spherical cell area and the caudal portion of the large spherical cell area. The descending branches of the basal turn project onto the dorsomedial two-thirds of the posteroventral nucleus (PVCN) with globular cell and octopus cell areas, and terminate in the dorsomedial portion of the central region of the dorsal cochlear nucleus (DCN). Terminals of the apical turn are associated with globular, small spherical and large spherical cells in the ventrolateral part of the AVCN, with globular cells, multipolar cells and a few octopus cells in the ventral PVCN, and with cells of the lateroventral extreme of the central region in the DCN. Lesions of the second and third turns result in degeneration in correspondingly intermediate regions of the cochlear nuclei. There is a predominance of the basal and second turn representation in the three major subdivisions of the cochlear nuclei except the anterior pole of the AVCN.
Zusammenfassung
An 16 Meerschweinchen wurden umschriebene Läsionen an der Cochlea gesetzt und die neurale Degeneration in der Cochlea, im Nervus cochlearis und im Cochleariskernkomplex mit Silberfärbungen nach Bodian und Schultze-Gros nachgewiesen. Dabei interessierten speziell die Projektion einzelner Windungen auf cytocarchitektonisch definierte Regionen der Cochleariskerne, wobei die Neuronenklassifikation nach Osen benutzt wurde. Die Rami ascendentes der Basalwindung enden im mediodoralen antero-ventralen Cochleariskern an Globular-Zellen, kleinen Rund-Zellen und im caudalen Teil der großen Rund-Zellregion. Die Rami descendentes der Basalwindung enden in den dorsalen zwei Dritteln des postero-ventralen Cochleariskerns an Globular- und Octopus-Zellen und im dorsomedialen Teil der Zentralregion des dorsalen Cochleariskerns. Fasern aus der Apexwindung enden im latero-ventralen Teil des AVCN an Globular-Zellen, kleinen und großen Rund-Zellen, und im ventralen Teil des PVCN an Globular-Zellen, multipolaren Zellen und einigen Octopus-Zellen sowie in der latero-ventralen Ecke der Zentralregion des DCN. Läsionen der zweiten und dritten Windungen führten zu Degenerationen in Regionen der Cochleariskerne, die zwischen den Endigungsstätten der Basis- und Apexwindung liegen. Die Dominanz der basalen und zweiten Windungen wurde in allen drei Unterabschnitten des Cochleariskernkomplexes mit Ausnahme des vordersten Poles des antero-ventralen Kerns beobachtet.
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Abbreviations
- AVCN:
-
Anteroventral cochlear nucleus
- cr:
-
central region
- DCN:
-
dorsal cochlear nucleus
- g:
-
granular layer
- gl:
-
globular cell
- lsc:
-
large spherical cell
- mo:
-
molecular layer
- mp:
-
multipolar cell
- oc:
-
octopus cell
- PVCN:
-
posteroventral cochlear nucleus
- py:
-
pyramidal cell layer
- s:
-
section
- ssc:
-
small spherical cell
- VCN:
-
ventral cochlear nucleus
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Guest-assistent 1969–1972; now Ass. Professor, Univ. Okinawa, Japan.
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Noda, Y., Pirsig, W. Anatomical projection of the cochlea to the cochlear nuclei of the guinea pig. Arch Otorhinolaryngol 208, 107–120 (1974). https://doi.org/10.1007/BF00453924
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DOI: https://doi.org/10.1007/BF00453924