Summary
Methods for the determination of glutathione in small epidermal and tumor fragments are compared. The best results were obtained by an enzymatic cycling technique. The total glutathione concentrations in basal cell epithelioma, squamous cell epithelioma, and verruca seborrhoeica were 2.08, 1.81, and 1.87 mg/g dry weight, respectively. In normal epidermis adjacent to the basal cell epitheliomas the concentration was 1.27 mg/g dry weight.
Zusammenfassung
Er werden die Bestimmungsmethoden für Glutathion in Epidermis-und Tumorfragmenten miteinander verglichen. Die besten Resultate wurden mit einer enzymatischen Cyclus-Technik erzielt. Die Konzentration des Gesamt-Glutathion in Basaliom, Spinaliome und Verruca seborrhoica betrug 2,08, 1,81 bzw 1,87 mg/g Trockengewicht. In der normalen, die Basaliome umgebenden Epidermis war die Konzentration 1,27 mg/g Trockengewicht.
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De Bersaques, J. Glutathione in human epidermal tumors. Arch Dermatol Res 269, 75–79 (1980). https://doi.org/10.1007/BF00404460
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DOI: https://doi.org/10.1007/BF00404460