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Growth factor antagonism studies with coccidia in tissue culture

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Summary

Using Eimeria tenella growing in monolayer cultures of chick kidney cells in vitro, interactions have been shown between thiamine and amprolium, pAB and sulphonamides, nicotinamide and 6-aminonicotinamide, and pyridoxine and 4-desoxypyridoxine. It was not possible to demonstrate effects involving biotin, riboflavine, purines or pyrimidines with a number of potential antagonists. It is suggested that the tissue culture system may be useful for studies of coccidial nutrition and in a search for metabolic antagonists for use as drugs.

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Ryley, J.F., Wilson, R.G. Growth factor antagonism studies with coccidia in tissue culture. Z. Parasitenk. 40, 31–34 (1972). https://doi.org/10.1007/BF00329613

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  • DOI: https://doi.org/10.1007/BF00329613

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