Summary
Injections of the wheat germ agglutinin — horse-radish peroxidase complex into the lateral reticular nucleus reveal that in addition to the well known contralateral rubroreticular connection, there is also a small but clear cut ipsilateral projection. Cells of various sizes participate in this ipsilateral pathway, and the retrogradely labelled neurons lie dispersed throughout the entire red nucleus.
Similar content being viewed by others
References
Bandler R (1978) Evidence for a bilateral “glomerular” projection from the red nucleus to the spinal nucleus of the trigeminal nerve in the cat. Neurosci Lett 8:211–217
Brodal A (1943) The cerebellar connections of the nucleus reticularis lateralis (nucleus funiculi lateralis) in rabbit and cat. Experimental investigations. Acta Psychiat Kbh 18:171–233
Brodal A (1957) The reticular formation of the brain stem. Anatomical aspects and functional correlations. The Henderson Trust Lecture. Oliver and Boyd, Edinburgh
Brodal A, Gogstad AC (1954) Rubrocerebellar connections. An experimental study in the cat. Anat Rec 118:455–486
Brodal P (1975) Demonstration of a somatotopically organized projection onto the paramedian lobule and the anterior lobe from the lateral reticular nucleus: and experimental study with the horseradish peroxidase method. Brain Res 95:221–239
Brodal P, Dietrichs E, Bjaalie JG, Nordby T, Walberg F (1983) Is lectin-coupled horseradish peroxidase taken up and transported by undamaged as well as by damaged fibers in the central nervous system? Brain Res 278:1–9
Brodal P, Marsala J, Brodal A (1967) The cerebral cortical projection to the lateral reticular nucleus in the cat, with special reference to the sensorimotor cortical areas. Brain Res 6:252–274
Bush HFM (1961) An antomical analysis of the white matter in the brain stem of the cat. Van Gorcum & Co NV, Assen
Cajal SR (1911) Histologie du système nerveux de l'homme et des vertébrès. Maloine, Paris
Condé-Courtine F (1980) Diversité morphologique et pluralisme des efférences du noyau rouge du chat. Application de la technique de marquage cellulaire par le transport rétrograde de la péroxydase du raifort. Thèse de doctorat ès sciences naturelles, l'Université de Paris, XI Centre d'Orsay, pp. 1–210
Corvaja N, Grofová I, Pompeiano O, Walberg F (1977) The lateral reticular nucleus in the cat. I. An experimental anatomical study of its spinal and supraspinal afferent connections. Neuroscience 2:537–553
Courville J (1966) Rubrobulbar fibres to the facial nucleus and the lateral reticular nucleus (nucleus of the lateral funiculus). An experimental study in the cat with silver impregnation methods. Brain Res 1:317–337
Dietrichs E (1983) Cerebellar nuclear afferents from the lateral reticular nucleus in the cat. Brain Res 288:320–324
Dietrichs E, Walberg F (1979) The cerebellar projection from the lateral reticular nucleus as studied with retrograde transport of horseradish peroxidase. Anat Embryol 155:273–290
Dietrichs E, Walberg F (1983) Cerebellar cortical afferents from the red nucleus in the cat. Exp Brain Res 50:353–358
Edwards SB (1972) The ascending and descending projections of the red nucleus in the cat: an experimental study using an autoradiographic tracing method. Brain Res 48:45–63
Gonatas NK, Harper C, Mizutani T, Gonatas JO (1979) Superior sensitivity of conjugates of horseradish peroxidase with wheat germ agglutinin for studies of retrograde axonal transport. J Histochem Cytochem 27:728–734
Hinnman A, Carpenter MB (1959) Efferent fiber projections of the red nucleus in the cat. J Comp Neurol 113:61–82
Hrycyshyn AW, Flumerfelt BA (1981) A light microscopic investigation of the afferent connections of the lateral reticular nucleus in the cat. J Comp Neurol 197:477–502
Künzle H (1973) The topographic organization of spinal afferents to the lateral reticular nucleus in the cat. J Comp Neurol 149:103–116
Künzle H (1975) Autoradiographic tracing of the cerebellar projections from the lateral reticular nucleus in the cat. Exp Brain Res 22:255–266
Künzle H, Wiesendanger M (1974) Pyramidal connections to the lateral reticular nucleus in the cat: a degeneration study. Acta Anat (Basel) 88:105–114
Martin GF, Dom R (1970) Rubrobulbar projections of the oposum. J Comp Neurol 139:199–214
Martin GF, Dom R, Katz S, King JS (1974) The organization of projection neurons in the opossum red nucleus. Brain Res 78:17–34
Matsushita M, Ikeda M (1976) Projections from the lateral reticular nucleus to the cerebellar cortex and nuclei in the cat. Exp Brain Res 24:403–421
Mesulam M-M (1978) Tetramethyl benzidine for horseradish peroxidase neurochemistry: a non-carcinogenic blue reaction-product with superior sensitivity for visualizing neural afferents and efferents. J Histochem Cytochem 26:106–117
Miller RA, Strominger NL (1973) Efferent connections of the red nucleus in the brain stem and spinal cord of the rhesus monkey. J Comp Neurol 152:327–346
Mizuno N, Mochizuki K, Akimoto C, Matsushima R, Nakamura Y (1973) Rubrobulbar projections in the rabbit. A light and electron microscopic study. J Comp Neurol 147:267–280
Probst M (1902) Experimentelle Untersuchungen über die Anatomie und Physiologie der Leitungsbahnen des Gehrinstammes. Arch Anat Physiol (Anat Abt) 147–254
Probst M (1903) Über die anatomischen und physiologischen Folgen der Halbseitendurchschneidung des Mittelhirns. Jb. Psychiat. Neurol. 24:219–325
Shieh JY, Leong SK, Wong WC (1983) Origin of the rubrospinal tract in neonatal, developing, and mature rats. J Comp Neurol 214:79–86
Trojanowski JQ, Gonatas JO, Gonatas NK (1981 a) A light- and electron-microscopic study of the intraneuronal transport of horseradish peroxidase and wheat germ agglutininperoxidase conjugates in the rat visual system. J Neurocytol 10:441–456
Trojanowski JQ, Gonatas JO, Gonatas NK (1981 b) Conjugates of horseradish peroxidase (HRP) with cholera toxin and wheat germ agglutinin are superior to free HRP as orthogradely transported markers. Brain Res 223:381–385
Trojanowski JQ, Gonatas JO, Gonatas NK (1982) Horseradish peroxidase (HRP) conjugates of cholera toxin and lectins are more sensitive retrogradely transported markers than free HRP. Brain Res 231:33–50
Walberg F (1952) The lateral reticular nucleus of the medulla oblongata in mammals. J Comp Neurol 96:283–343
Walberg F (1958) Descending connections to the lateral reticular nucleus. An experimental study in the cat. J Comp Neurol 109:363–389
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Qvist, H., Dietrichs, E. & Walberg, F. An ipsilateral projection from the red nucleus to the lateral reticular nucleus in the cat. Anat Embryol 170, 327–330 (1984). https://doi.org/10.1007/BF00318738
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00318738