Abstract
We report herein the case of a 77-year-old woman who was admitted to our hospital for further evaluation of an abnormal shadow in the right upper mediastinum that had been revealed by a routine chest X-ray. Computed tomography (CT) and magnetic resonance imaging (MRI) scans confirmed the presence of a thymic tumor, but did not show any evidence of invasion into the central vessels or adjacent structures. Thus, an extended thymectomy with resection of the tumor was performed. Microscopically, normal thymic tissue was found among the tumor cells, and a pathological diagnosis of well-differentiated liposarcoma was established. From the operative and microscopic findings, it is apparent that the tumor was related to the thymus. Postoperative irradiation of 60 Gy was delivered to the operative site and the patient has remained free of disease for 29 months since the operation.
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References
Russell WO, Cohen J, Enzinger F, Hajdu SI, Heise H, Martin RG, Meissner W, Miller WT, Schmitz RL, Suit HD (1977) A clinical and pathological staging system for soft tissue sarcomas. Cancer 40:1562–1570
Schweitzer DL, Aguam AS (1977) Primary liposarcoma of the mediastinum. Report of a case and review of the literature. J Thorac Cardiovasc Surg 74:83–97
Enzinger FM, Lattes R, Torloni H (1969) Histological typing of soft tissue tumors. International histological classification of tumors, no 3, World Health Organization, Geneva
Wada H, Teramatsu T (1982) Mediastinal tumors — a statistical nationwide report of 1546 cases between July 1975 and May 1979 in Japan (in Japanese with English abstract). Nippon Kyoubu Geka Gakkai Zasshi (J Jpn Assn Thorac Surg) 30:374–378
Wychulis AR, Payne WS, Clagett OT, Woolner LB (1971) Surgical treatment of mediastinal tumors. A 40-year experience. J Thorac Cardiovasc Surg 62:379–392
Enzinger FM, Weiss SW (1988) Soft tissue tumors. Mosby, St. Louis, pp 346–382
Razzuk MA, Urschel HC, Race GJ, Kingsley WB, Paulson DL (1971) Liposarcoma of the mediastinum. Case report and review of the literature. J Thorac Cardiovasc Surg 61:819–826
Kindblom LG, Save SJ (1979) The ultrastructure of liposarcoma. A study of 10 cases. Acta Pathol Microbiol Scand [Sect A] 87:109–121
Napolitano L (1963) The differentiation of white adipose cells. An electron microscope study. J Cell Biol 18:663–679
Lagace R, Jacob S, Seemeyer TA (1979) Myxoid liposarcoma. An electron microscopic study: Biological and histogenetic considerations. Virchows Arch [A] 384:159–172
Shibata K, Koga Y, Onitsuka T, Wake N, Ishii K, Sekiya R, Sumiyoshi A (1986) Primary liposarcoma of the mediastinum. A case report and review of the literature. Jpn J Surg 16:277–283
Okumori M, Mabuchi M, Nakagawa M (1983) Malignant thymoma associated with liposarcoma of the mediastinum — a case report. Jpn J Surg 13:512–518
Havlicek F, Rosai J (1984) A sarcoma of thymic stroma with features of liposarcoma. Am J Clin Pathol 82:217–224
Kagawa K, Masuda A, Tanaka K, Tatsumi A, Nonoyama A, Kagawa T (1986) Multicentric occurrence of liposarcoma. Report of a case and review of the literature (in Japanese with English abstract) Nippon Kyoubu Geka Gakkai Zasshi (J Jpn Assn Thorac Surg) 34:897–902
Wells HG (1940) Adipose tissue, a neglected subject. JAMA 114:2177–2183
Ackerman LV (1944) Multiple primary liposarcomas. Am J Pathol 20:789–798
Ito J, Mitsuhashi N, Okazaki A, Ikeda H, Kato M, Niibe H (1980) Radiation therapy of liposarcoma. A study of 11 cases (in Japanese with English abstract). Nippon Igaku Hoshasen Gakkai Zasshi (Nippon Acta Radiol) 40:445–452
Friedman M, Egan JW (1960) Irradiation of liposarcoma. Acta Radiol Suppl (Stockh) 54:225–239
Castleberry RP, Kelly DR, Wilson ER, Cain WS, Salter MR (1984) Childhood liposarcoma. Report of a case and review of the literature. Cancer 54:579–584
Tanaka M, Hizawa K, Tonai M (1974) Liposarcoma. A clinicopathological study on 136 cases based on the histological subtyping of WHO. Jpn J Cancer Clin 20:1036–1047
Enzinger FM, Winslow DJ (1962) Liposarcoma: a study of 103 cases. Virchows Arch [A] 335:367–388
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Sekine, Y., Hamaguchi, K., Miyahara, Y. et al. Thymus-related liposarcoma: Report of a case and review of the literature. Surg Today 26, 203–207 (1996). https://doi.org/10.1007/BF00311509
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DOI: https://doi.org/10.1007/BF00311509