Abstract
Plasma human growth hormone ([HGH]), adrenaline ([A]), noradrenaline ([NA]) and blood lactate ([La−]b) concentrations were measured during progressive, multistage exercise on a cycle ergometer in 12 endurance-trained athletes [aged 32.0 (SEM 2.0) years]. Exercise intensities (3 min each) were increased by 50 W until the subjects felt exhausted. Venous blood samples were taken after each intensity. The [HGH] and catecholamine concentrations increased negligibly during exercise of low to moderate intensities revealing an abrupt rise at the load corresponding to the lactate threshold ([La−]-T). Close correlations (P < 0.001) were found between [La−]b and plasma [HGH] (r = 0.64), [A] (r = 0.71) and [NA] (r = 0.81). The mean threshold exercise intensities for [HGH], [A] and [NA], detected by log-log transformation, [154 (SEM 19) W, 162 (SEM 15) W and 160 (SEM 17) W, respectively] were not significantly different from the [La−]-T [161 (SEM 12) W]. The results indicated that the threshold rise in plasma [HGH] followed the patterns of plasma catecholamine and blood lactate accumulation during progressive exercise in the endurancetrained athletes.
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References
Beaver W, Wasserman K, Whipp BJ (1985) Improved detection of lactate threshold during exercise using a log-log transformation. J Appl Physiol 59:1936–1940
Brooks GA (1985) Anaerobic threshold: review of the concept and direction for future research. Med Sci Sports Exerc 17:22–31
Brooks GA, Gregg SG (1988) Catecholamine stimulation during acure anemia increases exercise lactate production and decreases clearance. Med Sci Sports Exerc 20:S46
Chmura J, Nazar K, Kaciuba-Uscilko H (1994) Choice reaction time during graded exercise in relation to blood lactate and plasma catecholamine thresholds. Int J Sports Med 15:172–176
Chwalbinska-Moneta J, Robergs RA, Costill DL, Fink WJ (1989) Threshold for muscle lactate accumulation during progressive exercise. J Appl Physiol 66:2710–2716
Da Prada M, Zurcher G (1979) Radioenzymatic assay of plasma and urinary catecholamines in men and various animal species. Physiological and pharmacological applications. In: Albertini A, Da Prada M, Pescar A (eds) Radioimmunoassay of drugs and hormones in cardiovascular medicine. Elsevier/North Holland, Amsterdam, pp 112–119
Davis JA (1985) Anaerobic threshold: review of the concept and directions for future research. Med Sci Sports Exerc 17:6–18
Galbo H (1981) Endocrinology and metabolism in exercise. Int J Sports Med 2:203–211
Gordon SE, Kraemer WJ, Vos NH, Lynch JM, Knuttgen HG (1994) Effect of acid-base balance on the growth hormone response to acute high-intensity cycle exercise. J Appl Physiol 76:821–829
Gutmann I, Wahlefeld AW (1974) L-(+)-lactate determination with lactate dehydrogenase and NAD. In: Bergmayer HU (ed) Methods of enzymatic analysis, vol. 4. Academic Press, New York, pp 1464–1468
Hansen Ap (1971) Abnormal serum growth hormone response to exercise in normal and diabetic men. J Clin Invest 49: 1467–1478
Heck H, Mader A, Hess G, Mucke S, Muller R, Hollmann W (1985) Justification of the 4-mmol/1 lactate threshold. Int J Sports Med 6:117–130
Ivy JL, Chi MM-Y, Hintz CS, Sherman WM, Hellendall RP, Lowry OH (1987) Progressive metabolite changes in individual human muscle fibers with increasing work rates. Am J Physiol 252:C630-C639
Kjaer M (1989) Epinephrine and some other hormonal responses to exercise in man: with special reference to physical training. Int J Sports Med 10:2–15
Kjaer M, Secher NH, Bach FW, Sheikh S, Galbo H (1989) Hormonal and metabolic responses to exercise in humans: effect of sensory nervous blockade. Am J Physiol 257:E96-E101
Kozlowski S, Chwalbinska-Moneta J, Vigaš M, Kaciuba-Uscilko H, Nazar K (1983) Greater serum GH response to arm than to leg exercise performed at equivalent oxygen uptake. Eur J Appl Physiol 52:131–135
Lehmann M, Keul J, Huber G, Da Prada M (1981) Plasma catecholamines in trained and untrained volunteers during graduated exercise. Int J Sports Med 2:143–147
Mazzeo RS, Marshall P (1989) Influence of plasma catecholamines on the lactate threshold during graded exercise. J Appl Physiol 67:1319–1322
McCloskey DL, Mitchell JH (1972) Reflex cardiovascular and respiratory responses originating in exercising muscle. J Physiol (Lond) 224:173–186
Nilsson KO, Heding LG, Hökfelt B (1975) The influence of short term submaximal work on plasma concentration of catecholamines, pancreatic glucagon and growth hormone in man. Acta Endocrinol (copenh) 79:286–294
Podolin DA, Munger PA, Mazzeo RS (1991) Plasma catecholamine and lactate response during graded exercise with varied glycogen conditions. J Appl Physiol 71:1427–1433
Schneider DA, McGuiggin ME, Kamimori GH (1992) A comparison of the blood lactate and plasma catecholamine thresholds in untrained male subjects. Int J Sports Med 13:562–566
Sutton JR, Jones NL, Toews CJ (1976) Growth hormone secretion in acid-base alterations at rest and during exercise. Clin Sci Mol Med 50:241–247
Vanhelder WP, Casey K, Radomski MW (1987) Regulation of growth hormone during exercise by oxygen demand and availability. Eur J Appl Physiol 56:628–632
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Chwalbinska-Moneta, J., Krysztofiak, H., Ziemba, A. et al. Threshold increases in plasma growth hormone in relation to plasma catecholamine and blood lactate concentrations during progressive exercise in endurance-trained athletes. Europ. J. Appl. Physiol. 73, 117–120 (1996). https://doi.org/10.1007/BF00262819
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DOI: https://doi.org/10.1007/BF00262819