Summary
Spontaneous action potentials recorded from 126 neurons in the olfactory bulb of Salmo gairdneri show a higher tendency towards bursting patterns of activity than those shown in previous reports about other fish. Granule cells and periglomerular cells are more likely to fire in bursts than mitral cells. Natural chemical stimulation of the olfactory mucosa with amino acid solutions produced a unique pattern of excitatory and inhibitory responses across all units. Chi-square values were calculated for stimulatory effectiveness between forty-five pairs of odours. L-serine and L-alanine consistently showed a high degree of similarity with several other odours. The converse was true for GABA and L-histidine, although this pair had a high chi-square value when mutually compared. Enantiomeric pairs of amino acids were often found to have opposite stimulatory effects on bulbar units. These results are discussed in relation to the possible properties and configurations of odorant receptor sites for amino acids in the fish olfactory mucosa.
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References
Adrian, E.D.: The electrical activity of the mammalian olfactory bulb. Electroenceph. clin. Neurophysiol. 2, 377–388 (1950)
Døving, K.B.: Analysis of odour similarities from electrophysiological data. Acta physiol. scand. 68, 404–418 (1966a)
Døving, K.B.: Efferent influence upon the activity of single neurons in the olfactory bulb of the burbot. J. Neurophysiol. 29, 675–683 (1966b)
Døving, K.B.: The influence of olfactory stimulation upon the activity of central neurons in the burbot. Acta physiol. scand. 66, 290–299 (1966c)
Døving, K.B.: An electrophysiological study of odour similarities of homologous substances. J. Physiol. (Lond.) 186, 97–109 (1966d)
Døving, K.B., Hyvärinen, J.: Afferent and efferent influences on the activity pattern of single olfactory neurons. Acta physiol. scand. 75, 111–123 (1969)
Hara, T.J.: Olfactory responses to amino acids in rainbow trout. Comp. Biochem. Physiol. 44A, 407–416 (1972)
Hara, T.J., Law, Y.M.C., Hobden, B.R.: Comparison of the olfactory response to amino acids in rainbow trout, brook trout and whitefish. Comp. Biochem. Physiol. 45A, 969–977 (1973)
MacLeod, N.K.: Electrophysiological observations in the teleost olfactory bulb. Ph.D. Thesis. University of St. Andrews, Scotland 1975
MacLeod, N.K., Lowe, G.A.: Field potentials in the olfactory bulb of the rainbow trout (Salmo gairdneri): evidence for a dendrodendritic inhibitory pathway. Exp. Brain Res. 25, 255–266 (1976)
MacLeod, P.: Quality coding through neural response patterns. In: Transduction Mechanisms in Chemoreception. (ed. T.M. Poynder). London: Information Retrieval Ltd. 1974
Mathews, D.F.: Response patterns of single neurons in the tortoise olfactory epithelium and olfactory bulb. J. gen. Physiol. 60, 166–180 (1972)
Mathews, D.F.: Response patterns of single units in the olfactory bulb of the rat to odours. Brain Res. 47, 389–400 (1972a)
Mozell, M.M.: Spatial and temporal patterning. In: Handbook of Sensory Physiology. IV. Olfaction, (ed. L.M. Beidler). Berlin-Heidelberg-New York: Springer 1971
Ottoson, D.: The electro-olfactogram. In: Handbook of Sensory Physiology. IV. Olfaction. (ed. L.M. Beidler). Berlin-Heidelberg-New York: Springer 1971
Phillips, C.G., Powell, T.P.S., Shepherd, G.M.: Response of mitral cells to stimulation of the lateral olfactory tract in the rabbit. J. Physiol. (Lond.) 168, 65–88 (1963)
Sutterlin, A.M., Sutterlin, N.: Electrical responses of the olfactory epithelium of atlantic salmon (Salmo salar). J. Fish. Res. Bd. Canada 28, 565–572 (1971)
Suzuki, N., Tucker, D.: Amino acids as olfactory stimuli in freshwater catfish. Comp. Biochem. Physiol. 40A, 399–404 (1971)
Zippel, H.P., Breipohl, W.: Functions of the olfactory system in the goldfish (Carassius auratus). In: Olfaction and Taste V. (eds. D.A. Denton and J.P. Coghlan). pp. 163–167. New York: Academic Press 1975
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MacLeod, N.K. Spontaneous activity of single neurons in the olfactory bulb of the rainbow trout (Salmo gairdneri) and its modulation by olfactory stimulation with amino acids. Exp Brain Res 25, 267–278 (1976). https://doi.org/10.1007/BF00234018
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DOI: https://doi.org/10.1007/BF00234018