Summary
The distribution of serotonin- and vasopressin immunoreactivities in the suprachiasmatic nucleus (SCN) of four mammalian species was studied with the use of the modified peroxidase-antiperoxidase (PAP) method and antisera to serotonin and vasopressin. In the SCN of the rat, hamster and cat, we noted a large number of serotoninimmunoreactive nerve fibers particularly in the ventral area, where these fibers containing small varicosities (less than 1μm in diameter) formed a dense plexus. In the monkey (Macaca fuscata), however, only few serotonin-containing fibers were evident throughout the SCN. Vasopressin-immunoreactive somata and fibers were distributed in large numbers in the SCN of the rat, hamster, cat and monkey, especially in the dorsal nuclear area.
Regional and species-related differences of serotonin- and vasopressin distribution in the SCN were elucidated; possible functional differences between the ventral and dorsal areas of the SCN are discussed.
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This work was supported by grants (No. 56440022, No. 57214028) from the Ministry of Education, Science and Culture, Japan
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Ueda, S., Kawata, M. & Sano, Y. Identification of serotonin- and vasopressin immunoreactivities in the suprachiasmatic nucleus of four mammalian species. Cell Tissue Res. 234, 237–248 (1983). https://doi.org/10.1007/BF00213766
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DOI: https://doi.org/10.1007/BF00213766