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The human cardiac troponin I locus: assignment to chromosome 19p13.2–19q13.2

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Summary

The three major troponin I isoforms are encoded by separate genes and are expressed in a muscle-type-specific manner. A human cardiac troponin I cDNA has recently been isolated and used to establish the genomic location of the cardiac troponin I gene locus (designated TNNC1). By somatic cell hybrid analysis, the locus for TNNC1 maps to human chromosome 19 and can be localised to the region p13.2–q13.2

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Authors and Affiliations

  1. Human Genetic Resources, Imperial Cancer Research Fund, Clare Hall Laboratories, South Mimms, EN6 3LD, Potters Bar, Herts., UK

    Catriona MacGeoch & Nigel K. Spurr

  2. Department of Cardiothoracic Surgery, National Heart and Lung Institute, Dovehouse Street, SW7 6LY, London, UK

    Paul J. R. Barton, William J. Vallins & Pankaj Bhavsar

Authors
  1. Catriona MacGeoch
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  2. Paul J. R. Barton
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  3. William J. Vallins
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  4. Pankaj Bhavsar
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  5. Nigel K. Spurr
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MacGeoch, C., Barton, P.J.R., Vallins, W.J. et al. The human cardiac troponin I locus: assignment to chromosome 19p13.2–19q13.2. Hum Genet 88, 101–104 (1991). https://doi.org/10.1007/BF00204938

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  • DOI: https://doi.org/10.1007/BF00204938

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