Skip to main content
Log in

Diagnostic sonographic changes in the kidneys of 20 infants with congenital nephrotic syndrome of the Finnish type

  • Original articles
  • Pediatric radiology
  • Published:
European Radiology Aims and scope Submit manuscript

Abstract

A renal ultrasonographic study was performed on 20 infants with congenital nephrotic syndrome of the Finnish type. Follow-up ultrasonographic data were obtained on 13 of these patients. The renal lengths increased after 2 months of age. Later, at the age of approximately 18 months, the renal size had decreased again, and was within 2 SD of the predicted mean value. During the first 2 months of life the renal cortex was hyperechogenic and corticomedullary differentiation was clearly visible. Between 2 and 12 months of age the renal cortex was still hyperechogenic in all kidneys, but corticomedullary differentiation had disappeared from 10 of the 26 kidneys examined. After 12 months of age the kidney parenchyma was hyperechogenic and most kidneys had lost corticomedullary differentiation. Thus, the sonographic follow-up is one of the main diagnostic indices f congenital nephrotic syndrome.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Rapola J, Huttunen N-P, Hallman N (1992) Congenital and infantile nephrotic syndrome. In: Edelman CM, Jr (ed) Pediatric kidney disease, 2nd edn. Little Brown, Boston, pp 1291–1305

    Google Scholar 

  2. Koskimies O (1990) Genetics of congenital and early infantile nephrotic syndromes. In: Spitzer A, Avner ED (eds) Inheritance of kidney and urinary tract diseases, 1st edn. Kluwer, Boston, pp 131–138

    Google Scholar 

  3. Lanning P, Uhari M, Kouvelainen K, Lanning M (1989) Ultrasonic features of the congenital nephrotic syndrome of the Finnish type. Acta Paediatr Scand 78: 717

    Google Scholar 

  4. Han BK, Babcock DS (1985) Sonographic measurements and appearance of normal kidneys in children. AJR 145: 611

    Google Scholar 

  5. Holmberg C, Jalanko H, Koskimies O, Leijala M, Salmela K, Eklund B, Wikström S, Ahonen J (1990) Renal transplantation in children with congenital nephrotic syndrome of the Finnish type. Transplant Proc 22: 158

    Google Scholar 

  6. Mahan JD, Mauer SM, Sibley RK, Vernier RL (1984) Congenital nephrotic syndrome: evolution of medical management and results of renal transplantation. J Pediatr 105: 549

    Google Scholar 

  7. Graif M, Lison M, Strauss S, Manor A, Itzchak Y, Sack J (1982) Congenital nephrosis: ultrasonographic features. Pediatr Radiol 12: 154

    Google Scholar 

  8. Perale R, Talenti E, Lubrano G, Fassina A, Pavanello L, Rizzoni G (1988) Late ultrasonographic pattern in congenital nephrotic syndrome of Finnish type. Pediatr Radiol 18: 71

    Google Scholar 

  9. Alkrinawi S, Ben-Ezer Gradus D, Goldstein J, Barki Y (1989) Ultrasonographic pattern of congenital nephrotic syndrome of Finnish type. J Clin Ultrasound 17: 443

    Google Scholar 

  10. Currarino G, Stannard MW, Rutlege JC (1989) The sonolucent cortical rim in infantile polycystic kidneys (histologic correlation). J Ultrasound Med 8: 571

    Google Scholar 

  11. Fitch SJ, Stapleton FB (1986) Ultrasonographic features of glomerulocystic disease in infancy: similarity to infantile polycystic kidney disease. Pediatr Radiol 16: 400

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Correspondence to: O. Koskimies

Rights and permissions

Reprints and permissions

About this article

Cite this article

Saraga, M., Jääskeläinen, J. & Koskimies, O. Diagnostic sonographic changes in the kidneys of 20 infants with congenital nephrotic syndrome of the Finnish type. Eur. Radiol. 5, 49–54 (1995). https://doi.org/10.1007/BF00178081

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00178081

Key words

Navigation