Abstract
In this paper, the electric field generated in a conductive medium by needles pairs with inter-needle distance of 1 or 2 cm has been studied by means of 3D numerical models. The computational results have been correlated with experimental ones obtained in vitro on cultured cells. In particular, electroporation effect has been assessed on human osteosarcoma cell line MG63 cultured in monolayer. These results are helpful to evaluate the effect of the needle distance on the electric field distribution in cultured cells in terms of occurrence of reversible or irreversible electroporation.
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© 2016 Springer Science+Business Media Singapore
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Ongaro, A. et al. (2016). Effect of Electrode Distance in Electrochemotherapy: From Numerical Model to in Vitro Tests. In: Jarm, T., Kramar, P. (eds) 1st World Congress on Electroporation and Pulsed Electric Fields in Biology, Medicine and Food & Environmental Technologies. IFMBE Proceedings, vol 53. Springer, Singapore. https://doi.org/10.1007/978-981-287-817-5_37
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DOI: https://doi.org/10.1007/978-981-287-817-5_37
Publisher Name: Springer, Singapore
Print ISBN: 978-981-287-816-8
Online ISBN: 978-981-287-817-5
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