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Recent Developments in Quantum Dots Technologies as Effective Theranostic Tools Against Cancer

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Application of Quantum Dots in Biology and Medicine

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Abstract

Cancer, being a condition of unhindered cell growth ultimately leading to the death of the patient, is very prominent in modern society. Despite all the colloquial therapies to stop or prevent or cure cancer, it’s not curable to a full extent. These colloquial therapies used in the treatment of cancer involve chemotherapy, radiation therapy, etc., leading to very prominent side effects and more often than not, the recurrence of the disease. Thus, the need for an alternative to the treatment of cancer is of utmost and urgent requirement; in lieu of this fact, the quantum dots, which are semiconductor nanocrystals in the range of 1–10 nm are employed as a complete theranostic tool for the same. Recent progress in the quantum dots technology allows us to both image and kill cancer cells with high target specificity and minimum or no side effects. Various organic, as well as inorganic quantum dots, are being employed to cure cancer as it is or in conjugation with various biomarkers like peptides, transferrin, folic acid, etc. to increase target specificity and minimize side effects. Though a lot of research review, have been written over the past few years in the last decade, in this review we will be focusing on certain types of cancers and the treatments generally employed and their drawbacks, and the development with the current status of the quantum dots technology in the treatment of cancer and its drawbacks like cytotoxicity.

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Acknowledgements

The authors acknowledge the infrastructural facilities provided by NIT Rourkela.

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The authors declare no conflict of interest.

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  1. Department of Biotechnology and Medical Engineering, National Institute of Technology Rourkela, Rourkela, Odisha, 769008, India

    Aniket Mukherjee & Nandini Sarkar

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  1. Aniket Mukherjee
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  2. Nandini Sarkar
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Correspondence to Nandini Sarkar .

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  1. S. N. Bose National Centre for Basic Sciences, Kolkata, West Bengal, India

    Puspendu Barik

  2. Department of Chemistry, Rammohan College, University of Calcutta, Kolkata, West Bengal, India

    Samiran Mondal

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Mukherjee, A., Sarkar, N. (2022). Recent Developments in Quantum Dots Technologies as Effective Theranostic Tools Against Cancer. In: Barik, P., Mondal, S. (eds) Application of Quantum Dots in Biology and Medicine. Springer, Singapore. https://doi.org/10.1007/978-981-19-3144-4_6

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