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Genome-Wide Association Studies

  • Book
  • © 2019

Overview

  • Examines the utility of GWAS in a range of common diseases

  • Identifies limitations and means of overcoming them

  • Offers guidance on recruitment of samples and data analysis

  • Looks to the future of GWAS and what lies beyond

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Table of contents (8 chapters)

Keywords

About this book

This book examines the utility of genome-wide association studies (GWAS) in the era of next-generation sequencing and big data, identifies limitations and potential means of overcoming them, and looks to the future of GWAS and what may lay beyond. GWAS are among the most powerful tools for elucidating the genetic aspects of human and disease diversity. In Genome-Wide Association Studies, experts in the field explore in depth the impacts of GWAS on genomic research into a variety of common diseases, including cardiovascular, autoimmune, diabetic, cancer, and infectious diseases. The book will equip readers with a sound understanding both of the types of disease and phenotypes that are suited for GWAS and of the ways in which a road map resulting from GWAS can lead to the realization of personalized/precision medicine: functional analysis, drug seeds, pathway analysis, disease mechanism, risk prediction, and diagnosis.

Editors and Affiliations

  • Graduate School of Science, The University of Tokyo, Tokyo, Japan

    Tatsuhiko Tsunoda

  • BioResource Research Center, Tokyo Medical and Dental University, Tokyo, Japan

    Toshihiro Tanaka

  • Cancer Precision Medicine Center, Japanese Foundation for Cancer Research, Tokyo, Japan

    Yusuke Nakamura

About the editors

Tatsuhiko Tsunoda, Medical Research Institute, Tokyo Medical and Dental University, 1-5-45 Yushima, 113-8510 Tokyo, Japan

Toshihiro Tanaka, BioResource Research Center, Tokyo Medical and Dental University, 1-5-45 Yushima, 113-8510 Tokyo, 13 Japan

Yusuke Nakamura, Dept. of Medicine, University of Chicago, 900 E. 57th Street, 6240G, 60637 Chicago, IL, USA

Bibliographic Information

  • Book Title: Genome-Wide Association Studies

  • Editors: Tatsuhiko Tsunoda, Toshihiro Tanaka, Yusuke Nakamura

  • DOI: https://doi.org/10.1007/978-981-13-8177-5

  • Publisher: Springer Singapore

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Nature Singapore Pte Ltd. 2019

  • Hardcover ISBN: 978-981-13-8176-8Published: 14 November 2019

  • Softcover ISBN: 978-981-13-8179-9Published: 14 November 2020

  • eBook ISBN: 978-981-13-8177-5Published: 31 October 2019

  • Edition Number: 1

  • Number of Pages: IX, 209

  • Number of Illustrations: 2 b/w illustrations, 7 illustrations in colour

  • Topics: Human Genetics, Cancer Research, Immunology

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