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Metagenomics: Focusing on the Haystack

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Abstract

Metagenomics enables the genomics study of uncultured microorganisms, using inexpensive sequencing methods. This chapter provides a concise but comprehensive overview of the current computational methods in metagenomics and the recent progress made. The strategies, methods, software, and protocols generally used for metagenomics analysis of all environmental communities are discussed. Moreover, the challenges in the field of metagenomics, including applications where metagenomics analysis has opened up ways of investigating symbiosis, metabolic pathway construction in metagenomes, gene family enrichments, and disease association studies, are discussed.

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Authors and Affiliations

  1. Leiden University Medical Center, Leiden University, Leiden, The Netherlands

    Indu Khatri

  2. Lester & Sue Smith Breast Center & Department of Medicine, Baylor College of Medicine, Houston, TX, USA

    Meenakshi Anurag

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  1. Indu Khatri
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Correspondence to Meenakshi Anurag .

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  1. Department of Bioinformatics, Central University of South Bihar, Gaya, Bihar, India

    Asheesh Shanker

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Khatri, I., Anurag, M. (2018). Metagenomics: Focusing on the Haystack. In: Shanker, A. (eds) Bioinformatics: Sequences, Structures, Phylogeny . Springer, Singapore. https://doi.org/10.1007/978-981-13-1562-6_5

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