Abstract
Phase contrast magnetic resonance imaging (PC MRI) and the computational fluid dynamics (CFD) are two of the most important technologies in the investigation on the velocity field in blood vessels in vivo. In order to quantitatively compare the differences between the two methods, the blood flow velocity measurements based on PC MRI and patient-specific CFD were conducted at internal carotid artery from 9 healthy volunteers. The 3D velocity field calculated from PC MRI data were compared with CFD simulation in 5 planes covering the carotid siphon. Then the resistance index (RI), and errors in the magnitude and direction of velocity were calculated between the two methods. The results showed that the flow patterns of PC MRI and CFD were similar, and the velocity distribution and RI was in good agreement. But there were significant differences in the velocity magnitude near the posterior knee and vessel wall, while the directional error was larger at the center of the artery. These comparison between PC MRI and CFD may guide the development of CFD technology and improve its accuracy.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Macdonald, M.E.: Cerebrovascular MRI: a review of state-of-the-art approaches, methods and techniques. Nmr in Biomedicine 28(7), 767–791 (2015).
Goubergrits, L.: MRI-based computational fluid dynamics for diagnosis and treatment prediction: Clinical validation study in patients with coarctation of aorta. Journal of Magnetic Resonance Imaging 41(4), 909–16 (2015).
Lotz, J.: Cardiovascular Flow Measurement with Phase-Contrast MR Imaging: Basic Facts and Implementation. Radiographics A Review Publication of the Radiological Society of North America Inc 22(22), 651–671 (2002).
Hofman, M.B.M.: In Vivo Validation of Magnetic Resonance Blood Volume Flow Measurements with Limited Spatial Resolution in Small Vessels. Magnetic Resonance in Medicine 33(6), 778–784 (1995).
Alperin, N.: Hemodynamically independent analysis of cerebrospinal fluid and brain motion observed with dynamic phase contrast MRI. Magnetic Resonance in Medicine 35(35), 741–754 (1996).
Spilt A.: Reproducibility of total cerebral blood flow measurements using phase contrast magnetic resonance imaging. Journal of Magnetic Resonance Imaging 16(1), 1–5 (2010).
Bardan, G.: Simple patient-based transmantle pressure and shear estimate from cine phase-contrast MRI in cerebral aqueduct. IEEE Transactions on Biomedical Engineering 59(10), 2874–2883 (2012).
Harloff, A.: Comparison of blood flow velocity quantification by 4D flow MR imaging with ultrasound at the carotid bifurcation. American Journal of Neuroradiology 34(7), 1407–1413 (2013).
Pekkan, K.: In Vitro Hemodynamic Investigation of the Embryonic Aortic Arch at Late Gestation. Journal of Biomechanics 41(8), 1697–1706 (2008).
Leuprecht, A.: Blood flow in the human ascending aorta: a combined MRI and CFD study. Journal of Engineering Mathematics 47(3), 387–404 (2003).
Zhang, C.: Flow patterns and wall shear stress distribution in human internal carotid arteries: the geometric effect on the risk for stenoses. Journal of Biomechanics 45(1), 83–89 (2012).
Zhang, C.: Geometric classification of the carotid siphon: association between geometry and stenoses. Surgical and Radiologic Anatomy 35(5), 385–394 (2013).
Ali, S.F.: Velocity Measurement in Carotid Artery: Quantitative Comparison of Time-Resolved 3D Phase-Contrast MRI and Image-based Computational Fluid Dynamics. Iranian Journal of Radiology 12(3), e18286 (2015).
Harloff, A.: 3D blood flow characteristics in the carotid artery bifurcation assessed by flow-sensitive 4D MRI at 3T. Magnetic Resonance in Medicine 61(1), 65–74 (2009).
Van, O.P.: 3D cine phase-contrast MRI at 3T in intracranial aneurysms compared with patient-specific computational fluid dynamics. American Journal of Neuroradiology 34(9), 1785–1791 (2013).
Cebral, J.R.: Hemodynamics in Normal Cerebral Arteries: Qualitative Comparison of 4D Phase-Contrast Magnetic Resonance and Image-Based Computational Fluid Dynamics. Journal of Engineering Mathematics 64(4), 367–378 (2009).
Acknowledgements
This work was supported by National Natural Science Foundation (No. 11672026 and No. 11302019), and State Key Laboratory of Virtual Reality Technology and Systems.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Ethics declarations
The authors declare that they have no conflict of interest.
Statement of Informed Consent Informed consent was obtained from all individual participants included in the study.
Protection of Human Subjects and Animals in Research All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
Rights and permissions
Copyright information
© 2019 Springer Nature Singapore Pte Ltd.
About this paper
Cite this paper
Zhang, C. et al. (2019). Velocity Measurement at Carotid Siphon: Quantitative Comparison of Phase Contrast MRI and Computational Fluid Dynamics. In: Lhotska, L., Sukupova, L., Lacković, I., Ibbott, G.S. (eds) World Congress on Medical Physics and Biomedical Engineering 2018. IFMBE Proceedings, vol 68/1. Springer, Singapore. https://doi.org/10.1007/978-981-10-9035-6_92
Download citation
DOI: https://doi.org/10.1007/978-981-10-9035-6_92
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-10-9034-9
Online ISBN: 978-981-10-9035-6
eBook Packages: EngineeringEngineering (R0)