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Cell Culture and Observation on Microfluidics

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Cell Analysis on Microfluidics

Part of the book series: Integrated Analytical Systems ((ANASYS))

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Abstract

Recent advances in microfluidic systems have led to the development of on-chip culture and observation. The on-chip culture offers several advantages over conventional in vitro culture methods: Reduced cell and reagent consumption, more accurate mimicking of in vivo cellular microenvironment, integrating function modules and controllable mechanical and chemical factors. These advantages support the microfluidic applications in biological science, especially for cellular dynamic study. Based on transparent characteristics of chip substrate, the microfluidic devices can be easily coupled to cell imaging methods and realize bio-application in cellomics. In this chapter, we introduce the development of microfluidic culture and how the microfluidic devices work in cell observations, especially for cell biology .

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Authors and Affiliations

  1. School of Science, Beijing University of Chemical Technology, Beijing, 100029, China

    Linglu Yi

  2. Department of Chemistry, Tsinghua University, Beijing, 100084, People’s Republic of China

    Linglu Yi & Jin-Ming Lin

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  1. Linglu Yi
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  2. Jin-Ming Lin
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    Jin-Ming Lin

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Yi, L., Lin, JM. (2018). Cell Culture and Observation on Microfluidics. In: Lin, JM. (eds) Cell Analysis on Microfluidics. Integrated Analytical Systems. Springer, Singapore. https://doi.org/10.1007/978-981-10-5394-8_4

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