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Transcriptomics and Gene Regulation

  • Book
  • © 2016

Overview

Editors:
  1. Jiaqian Wu

    1. Center for Stem Cell and Regenerati, The Vivian L. Smith Department of N, HOUSTON, USA

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  • Focuses on modern computational and statistical tools
  • Introduces state of the art technologies for translational bioinformatics
  • Provides applications of technology
  • Includes supplementary material: sn.pub/extras

Part of the book series: Translational Bioinformatics (TRBIO, volume 9)

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Table of contents (7 chapters)

  1. Front Matter

    Pages i-x
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  2. The Analyses of Global Gene Expression and Transcription Factor Regulation

    • Raquel Cuevas Diaz Duran, Sudheer Menon, Jiaqian Wu
    Pages 1-35

  3. Global Approaches to Alternative Splicing and Its Regulation—Recent Advances and Open Questions

    • Yun-Hua Esther Hsiao, Ashley A. Cass, Jae Hoon Bahn, Xianzhi Lin, Xinshu Xiao
    Pages 37-71

  4. Long Noncoding RNAs: Critical Regulators for Cell Lineage Commitment in the Central Nervous System

    • Xiaomin Dong, Naveen Reddy Muppani, Jiaqian Wu
    Pages 73-97

  5. Gene Expression Models of Signaling Pathways

    • Jeffrey T. Chang
    Pages 99-113

  6. From Gene Expression to Disease Phenotypes: Network-Based Approaches to Study Complex Human Diseases

    • Quanwei Zhang, Wen Zhang, Rubén Nogales-Cadenas, Jhin-Rong Lin, Ying Cai, Zhengdong D. Zhang
    Pages 115-140

  7. Introduction to Isoform Sequencing Using Pacific Biosciences Technology (Iso-Seq)

    • Manuel L. Gonzalez-Garay
    Pages 141-160

  8. Systematic and Integrative Analysis of Gene Expression to Identify Feature Genes Underlying Human Diseases

    • Zixing Wang, Wenlong Xu, Yin Liu
    Pages 161-185
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Keywords

About this book


This volume focuses on modern computational and statistical tools for translational gene expression and regulation research to improve prognosis, diagnostics, prediction of severity, and therapies for human diseases. It introduces some of state of the art technologies as well as computational and statistical tools for translational bioinformatics in the areas of gene transcription and regulation, including the tools for next generation sequencing analyses, alternative spicing, the modeling of signaling pathways, network analyses in predicting disease genes, as well as protein and gene expression data integration in complex human diseases etc. The book is particularly useful for researchers and students in the field of molecular biology, clinical biology and bioinformatics, as well as physicians etc.  Dr. Jiaqian Wu is assistant professor in the Vivian L. Smith Department of Neurosurgery and Center for Stem Cell and Regenerative Medicine, University of Texas Health Science Centre, Houston, TX, USA.​


Editors and Affiliations

  • Center for Stem Cell and Regenerati, The Vivian L. Smith Department of N, HOUSTON, USA

    Jiaqian Wu

Bibliographic Information

  • Book Title: Transcriptomics and Gene Regulation

  • Editors: Jiaqian Wu

  • Series Title: Translational Bioinformatics

  • DOI: https://doi.org/10.1007/978-94-017-7450-5

  • Publisher: Springer Dordrecht

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media Dordrecht 2016

  • Hardcover ISBN: 978-94-017-7448-2Published: 28 October 2015

  • Softcover ISBN: 978-94-024-0434-0Published: 23 August 2016

  • eBook ISBN: 978-94-017-7450-5Published: 17 November 2015

  • Series ISSN: 2213-2775

  • Series E-ISSN: 2213-2783

  • Edition Number: 1

  • Number of Pages: X, 185

  • Number of Illustrations: 62 b/w illustrations, 2 illustrations in colour

  • Topics: Bioinformatics, Gene Expression, Neurosciences

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